RT Journal Article SR Electronic(1) A1 Piralla, A. A1 Daleno, C. A1 Girello, A. A1 Esposito, S. A1 Baldanti, F.YR 2015 T1 Circulation of two Enterovirus C105 (EV-C105) lineages in Europe and Africa JF Journal of General Virology, VO 96 IS 6 SP 1374 OP 1379 DO https://doi.org/10.1099/vir.0.000088 PB Microbiology Society, SN 1465-2099, AB The coding sequences of five human enterovirus (HEV)-C genotype 105 strains recovered in Italy, Romania and Burundi from patients with upper and lower respiratory tract infections were analysed and phylogenetically compared with other circulating HEV-C strains. The EV-C105 was closely related to EV-C109 and EV-C118 strains. The European strains were similar to other circulating EV-C105 strains, while the two African EV-C105 clustered in separate bootstrap-supported (>0.90) branches of the P2 and P3 region trees. Minor inconsistencies in the clustering pattern of EV-C105 in the capsid region (P1) and non-capsid region (P3) suggest that recombination may have occurred in EV-C105 group B viruses. In conclusion, phylogenetic analysis revealed the circulation of two distinct EV-C105 lineages in Europe and Africa. A different pattern of evolution could be hypothesized for the two EV-C105 lineages., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/vir.0.000088