1887

Abstract

Over recent decades, metagenomic studies have expanded the number of newly described, often unclassified, viruses within the family . Using broad-spectrum circovirus and cyclovirus PCRs, we characterized a novel circo-like virus in mosquitoes from Germany whose main putative ORFs shared very low amino acid identity with those of previously characterized circoviruses and cycloviruses. Phylogenetic and genetic distance analysis revealed that this new virus species defined, together with previously described mosquito- and bat faeces-derived circo-like viruses, a different genus, tentatively called , within the family . We further demonstrated that viruses of the putative genus all shared a genomic organization that was unique among the family . Further investigations are needed to determine the host range, tissue tropism and transmission route(s). This report increases the current knowledge of the genetic diversity and evolution of the members of the family .

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2015-04-01
2021-06-24
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