@article{mbs:/content/journal/jgv/10.1099/jgv.0.001758, author = "Fiege, Jessica K. and Langlois, Ryan A.", title = "Embracing the heterogeneity of natural viruses in mouse studies", journal= "Journal of General Virology", year = "2022", volume = "103", number = "6", pages = "", doi = "https://doi.org/10.1099/jgv.0.001758", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.001758", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "dirty mice", keywords = "virome", keywords = "microbiome", eid = "001758", abstract = "Animal models are a critical tool in modern biology. To increase reproducibility and to reduce confounding variables modern animal models exclude many microbes, including key natural commensals and pathogens. Here we discuss recent strategies to incorporate a natural microbiota to laboratory mouse models and the impacts the microbiota has on immune responses, with a focus on viruses.", }