Members of the family produce enveloped virions containing a linear negative-sense non-segmented RNA genome of about 9 kb. Bornaviruses are found in mammals, birds, reptiles and fish. The most-studied viruses with public health and veterinary impact are Borna disease virus 1 and variegated squirrel bornavirus 1, both of which cause fatal encephalitis in humans. Several orthobornaviruses cause neurological and intestinal disorders in birds, mostly parrots. Endogenous bornavirus-like sequences occur in the genomes of various animals. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family , which is available at ictv.global/report/bornaviridae.

This study was supported by the:
  • National Institute of Allergy and Infectious Diseases (Award HHSN272201800013C)
    • Principle Award Recipient: JensH. Kuhn
  • Bundesministerium für Bildung und Forschung (Award 01KI2005B)
    • Principle Award Recipient: RubbenstrothDennis
  • Wellcome Trust (Award WT108418AIA)
    • Principle Award Recipient: ICTVConsortium

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