RT Journal Article SR Electronic(1) A1 Magnius, Lars A1 Mason, William S. A1 Taylor, John A1 Kann, Michael A1 Glebe, Dieter A1 Dény, Paul A1 Sureau, Camille A1 Norder, Heléne A1 ICTV Report ConsortiumYR 2020 T1 ICTV Virus Taxonomy Profile: Hepadnaviridae JF Journal of General Virology, VO 101 IS 6 SP 571 OP 572 DO https://doi.org/10.1099/jgv.0.001415 PB Microbiology Society, SN 1465-2099, AB The family Hepadnaviridae comprises small enveloped viruses with a partially double-stranded DNA genome of 3.0–3.4 kb. All family members express three sets of proteins (preC/C, polymerase and preS/S) and replication involves reverse transcription within nucleocapsids in the cytoplasm of hepatocytes. Hepadnaviruses are hepatotropic and infections may be transient or persistent. There are five genera: Parahepadnavirus, Metahepadnavirus, Herpetohepadnavirus, Avihepadnavirus and Orthohepadnavirus. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hepadnaviridae, which is available at ictv.global/report/hepadnaviridae., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.001415