The family comprises small enveloped viruses with a partially double-stranded DNA genome of 3.0–3.4 kb. All family members express three sets of proteins (preC/C, polymerase and preS/S) and replication involves reverse transcription within nucleocapsids in the cytoplasm of hepatocytes. Hepadnaviruses are hepatotropic and infections may be transient or persistent. There are five genera: , , and . This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family which is available at ictv.global/report/hepadnaviridae.

This study was supported by the:
  • Wellcome Trust (GB) (Award WT108418AIA)
    • Principle Award Recipient: ICTV Consortium
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.

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