Birnaviridae is a family of viruses with bi-segmented dsRNA genomes totalling about 6 kbp forming icosahedral, non-enveloped virions. The family includes four genera, members of three of which (Aquabirnavirus, Avibirnavirus and Blosnavirus) infect vertebrates (excluding mammals), whereas members of the fourth genus (Entomobirnavirus) infect insects. Each genus includes 1–3 species. Infectious pancreatic necrosis virus of salmonids and infectious bursal disease virus of poultry are two economically important birnaviruses. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of Birnaviridae, which is available at www.ictv.global/report/birnaviridae.
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HjalmarssonA, CarlemalmE, EverittE. Infectious pancreatic necrosis virus: identification of a VP3-containing ribonucleoprotein core structure and evidence for O-linked glycosylation of the capsid protein VP2. J Virol1999; 73:3484–3490[PubMed]
GrahamSC, SarinLP, BaharMW, MyersRA, StuartDI et al. The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment. PLoS Pathog2011; 7:e1002085 [View Article][PubMed]
BirghanC, MundtE, GorbalenyaAE. A non-canonical lon proteinase lacking the ATPase domain employs the Ser-Lys catalytic dyad to exercise broad control over the life cycle of a double-stranded RNA virus. EMBO J2000; 19:114–123 [View Article][PubMed]
GorbalenyaAE, PringleFM, ZeddamJL, LukeBT, CameronCE et al. The palm subdomain-based active site is internally permuted in viral RNA-dependent RNA polymerases of an ancient lineage. J Mol Biol2002; 324:47–62 [View Article][PubMed]
PanJ, VakhariaVN, TaoYJ. The structure of a birnavirus polymerase reveals a distinct active site topology. Proc Natl Acad Sci USA2007; 104:7385–7390 [View Article][PubMed]
DulwichKL, GiotisES, GrayA, NairV, SkinnerMA et al. Differential gene expression in chicken primary B cells infected ex vivo with attenuated and very virulent strains of infectious bursal disease virus (IBDV). J Gen Virol2017; 98:2918–2930 [View Article][PubMed]
GibratJF, MariadassouM, BoudinotP, DelmasB. Analyses of the radiation of birnaviruses from diverse host phyla and of their evolutionary affinities with other double-stranded RNA and positive strand RNA viruses using robust structure-based multiple sequence alignments and advanced phylogenetic methods. BMC Evol Biol2013; 13:154 [View Article][PubMed]