1887

Abstract

The Togaviridae is a family of small, enveloped viruses with single-stranded, positive-sense RNA genomes of 10–12 kb. Within the family, the genus Alphavirus includes a large number of diverse species, while the genus Rubivirus includes the single species Rubella virus. Most alphaviruses are mosquito-borne and are pathogenic in their vertebrate hosts. Many are important human and veterinary pathogens (e.g. chikungunya virus and eastern equine encephalitis virus). Rubella virus is transmitted by respiratory routes among humans. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Togaviridae, which is available at www.ictv.global/report/togaviridae.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/jgv.0.001072
2018-05-10
2019-09-18
Loading full text...

Full text loading...

/deliver/fulltext/jgv/99/6/761.html?itemId=/content/journal/jgv/10.1099/jgv.0.001072&mimeType=html&fmt=ahah

References

  1. Li L, Jose J, Xiang Y, Kuhn RJ, Rossmann MG. Structural changes of envelope proteins during alphavirus fusion. Nature 2010; 468: 705– 708 [CrossRef] [PubMed]
    [Google Scholar]
  2. Mangala Prasad V, Klose T, Rossmann MG. Assembly, maturation and three-dimensional helical structure of the teratogenic rubella virus. PLoS Pathog 2017; 13: e1006377 [CrossRef] [PubMed]
    [Google Scholar]
  3. Kuhn RJ. Togaviridae. In Knipe DM, Howley PM. (editors) Fields' Virology Philadelphia, USA: Lippincott Williams & Wilkins; 2013; pp. 629– 650
    [Google Scholar]
  4. Rupp JC, Sokoloski KJ, Gebhart NN, Hardy RW. Alphavirus RNA synthesis and non-structural protein functions. J Gen Virol 2015; 96: 2483– 2500 [CrossRef] [PubMed]
    [Google Scholar]
  5. Frey TK. Molecular biology of rubella virus. Adv Virus Res 1994; 44: 69– 160 [PubMed] [Crossref]
    [Google Scholar]
  6. Nasar F, Palacios G, Gorchakov RV, Guzman H, da Rosa AP et al. Eilat virus, a unique alphavirus with host range restricted to insects by RNA replication. Proc Natl Acad Sci USA 2012; 109: 14622– 14627 [CrossRef] [PubMed]
    [Google Scholar]
  7. Hermanns K, Zirkel F, Kopp A, Marklewitz M, Rwego IB et al. Discovery of a novel alphavirus related to Eilat virus. J Gen Virol 2017; 98: 43– 49 [CrossRef] [PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/jgv.0.001072
Loading
/content/journal/jgv/10.1099/jgv.0.001072
Loading

Data & Media loading...

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error