%0 Journal Article %A Suzuki, Nobuhiro %A Ghabrial, Said A. %A Kim, Kook-Hyung %A Pearson, Michael %A Marzano, Shin-Yi L. %A Yaegashi, Hajime %A Xie, Jiatao %A Guo, Lihua %A Kondo, Hideki %A Koloniuk, Igor %A Hillman, Bradley I. %A ICTV Report Consortium %T ICTV Virus Taxonomy Profile: Hypoviridae %D 2018 %J Journal of General Virology, %V 99 %N 5 %P 615-616 %@ 1465-2099 %R https://doi.org/10.1099/jgv.0.001055 %K ICTV Report %K Hypoviridae %K Taxonomy %I Microbiology Society, %X The Hypoviridae, comprising one genus, Hypovirus, is a family of capsidless viruses with positive-sense, ssRNA genomes of 9.1–12.7 kb that possess either a single large ORF or two ORFs. The ORFs appear to be translated from genomic RNA by non-canonical mechanisms, i.e. internal ribosome entry site-mediated and stop/restart translation. Hypoviruses have been detected in ascomycetous or basidiomycetous filamentous fungi, and are considered to be replicated in host Golgi-derived, lipid vesicles that contain their dsRNA as a replicative form. Some hypoviruses induce hypovirulence to host fungi, while others do not. This is a summary of the current ICTV report on the taxonomy of the Hypoviridae, which is available at www.ictv.global/report/hypoviridae. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.001055