@article{mbs:/content/journal/jgv/10.1099/jgv.0.001041, author = "Van Doorslaer, Koenraad and Kraberger, Simona and Austin, Charlotte and Farkas, Kata and Bergeman, Melissa and Paunil, Emma and Davison, William and Varsani, Arvind", title = "Fish polyomaviruses belong to two distinct evolutionary lineages", journal= "Journal of General Virology", year = "2018", volume = "99", number = "4", pages = "567-573", doi = "https://doi.org/10.1099/jgv.0.001041", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.001041", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", keywords = "Antarctica", keywords = "Trematomus bernacchii", keywords = "emerald notothen", keywords = "Polyomaviridae", abstract = "The Polyomaviridae is a diverse family of circular double-stranded DNA viruses. Polyomaviruses have been isolated from a wide array of animal hosts. An understanding of the evolutionary and ecological dynamics of these viruses is essential to understanding the pathogenicity of polyomaviruses. Using a high throughput sequencing approach, we identified a novel polyomavirus in an emerald notothen (Trematomus bernacchii) sampled in the Ross sea (Antarctica), expanding the known number of fish-associated polyomaviruses. Our analysis suggests that polyomaviruses belong to three main evolutionary clades; the first clade is made up of all recognized terrestrial polyomaviruses. The fish-associated polyomaviruses are not monophyletic, and belong to two divergent evolutionary lineages. The fish viruses provide evidence that the evolution of the key viral large T protein involves gain and loss of distinct domains.", }