1887

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Volume 98, Issue 10

V2 from a curtovirus is a suppressor of post-transcriptional gene silencing Free

Abstract

The suppression of gene silencing is a key mechanism for the success of viral infection in plants. DNA viruses from the family encode several proteins that suppress transcriptional and post-transcriptional gene silencing (TGS/PTGS). In , the most abundant genus of this family, three out of six genome-encoded proteins, namely C2, C4 and V2, have been shown to suppress PTGS, with V2 being the strongest PTGS suppressor in transient assays. (BCTV), the model species for the genus, is able to infect the widest range of plants among geminiviruses. In this genus, only one protein, C2/L2, has been described as inhibiting PTGS. We show here that, despite the lack of sequence homology with its begomoviral counterpart, BCTV V2 acts as a potent PTGS suppressor, possibly by impairing the RDR6 (RNA-dependent RNA polymerase 6)/suppressor of gene silencing 3 (SGS3) pathway.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): BCTV , Geminivirus , RDR6 , RNA silencing , silencing suppressor and V2
© 2017 The Authors
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2017-10-01
2024-04-19
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V2 from a curtovirus is a suppressor of post-transcriptional gene silencing
J. Gen. Virol. 98, 2607 (2017); https://doi.org/10.1099/jgv.0.000933
/content/journal/jgv/10.1099/jgv.0.000933
/content/journal/jgv/10.1099/jgv.0.000933
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