1887

Abstract

The Bunyaviridae family is made up of a diverse range of viruses, some of which cause disease and are a cause for concern in human and veterinary health. Here, we report the genomic and antigenic characterization of five previously uncharacterized bunyaviruses. Based on their ultrastructure, antigenic relationships and phylogenomic relationships, the five viruses are classified as members of the Orthobunyavirus genus. Three are viruses in the California encephalitis virus serogroup and are related to Trivittatus virus; the two others are most similar to the Mermet virus in the Simbu serogroup, and to the Tataguine virus, which is not currently assigned to a serogroup. Each of these five viruses was pathogenic to newborn mice, indicating their potential to cause illness in humans and other animals.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/jgv.0.000899
2017-09-09
2019-10-20
Loading full text...

Full text loading...

/deliver/fulltext/jgv/98/9/2258.html?itemId=/content/journal/jgv/10.1099/jgv.0.000899&mimeType=html&fmt=ahah

References

  1. Plyusnin A, Beaty BJ, Elliott RM, Goldbach R, Korelink R et al. Family Bunyaviridae. In King A, Adams MJ, Carstens EB, Fefkowitz EJ. (editors) Virus Taxonomy Ninth Report of the International Committee on Taxonomy of Viruses San Diego: Elsevier Academic Press; 2012
    [Google Scholar]
  2. Briese T, Calisher CH, Higgs S. Viruses of the family Bunyaviridae: are all available isolates reassortants?. Virology 2013;446:207–216 [CrossRef][PubMed]
    [Google Scholar]
  3. Ladner JT, Savji N, Lofts L, Travassos da Rosa A, Wiley MR et al. Genomic and phylogenetic characterization of viruses included in the manzanilla and oropouche species complexes of the genus Orthobunyavirus, family Bunyaviridae. J Gen Virol 2014;95:1055–1066 [CrossRef][PubMed]
    [Google Scholar]
  4. Navarro JC, Giambalvo D, Hernandez R, Auguste AJ, Tesh RB et al. Isolation of Madre de Dios virus (Orthobunyavirus; Bunyaviridae), an Oropouche virus species reassortant, from a monkey in Venezuela. Am J Trop Med Hyg 2016;95:328–338 [CrossRef][PubMed]
    [Google Scholar]
  5. Palacios G, da Rosa AT, Savji N, Sze W, Wick I et al. Aguacate virus, a new antigenic complex of the genus Phlebovirus (family Bunyaviridae). J Gen Virol 2011;92:1445–1453 [CrossRef][PubMed]
    [Google Scholar]
  6. Gerrard SR, Li L, Barrett AD, Nichol ST. Ngari virus is a Bunyamwera virus reassortant that can be associated with large outbreaks of hemorrhagic fever in Africa. J Virol 2004;78:8922–8926 [CrossRef][PubMed]
    [Google Scholar]
  7. Elliott RM. Orthobunyaviruses: recent genetic and structural insights. Nat Rev Microbiol 2014;12:673–685 [CrossRef][PubMed]
    [Google Scholar]
  8. Arbovirus Catalog [Internet] December 13, 2013; Atlanta, GA: Centers for Disease Control and Prevention; Available from wwwn.cdc.gov/arbocat/VirusBrowser.aspx
  9. Fagbami AH, Tomori O. Tataguine virus isolations from humans in Nigeria, 1971–1975. Trans R Soc Trop Med Hyg 1981;75:788 [CrossRef][PubMed]
    [Google Scholar]
  10. Dyer JL. Characterization of unidentified viruses from Florida. Graduate Theses and Dissertations 2010
    [Google Scholar]
  11. Shchetinin AM, Lvov DK, Deriabin PG, Botikov AG, Gitelman AK et al. Genetic and phylogenetic characterization of Tataguine and Witwatersrand viruses and other orthobunyaviruses of the Anopheles A, Capim, Guamá, Koongol, Mapputta, Tete, and Turlock serogroups. Viruses 2015;7:5987–6008 [CrossRef][PubMed]
    [Google Scholar]
  12. Leduc JW. Epidemiology and ecology of the California serogroup viruses. Am J Trop Med Hyg 1987;37:60S–68S [CrossRef][PubMed]
    [Google Scholar]
  13. Shope RE, Meegan JM. Arboviruses. In Evans AS, Kaslow RA. (editors) Viral Infection of Human: Epidemiology and Control, 4th ed. USA: Plenum Press; 1997; pp.167–168
    [Google Scholar]
  14. Campbell WP, Huang C. Sequence comparisons of medium RNA segment among 15 California serogroup viruses. Virus Res 1999;61:137–144 [CrossRef][PubMed]
    [Google Scholar]
  15. Huang C, Shope RE, Spargo B, Campbell WP. The S RNA genomic sequences of Inkoo, San Angelo, Serra do Navio, south river and Tahyna bunyaviruses. J Gen Virol 1996;77:1761–1768 [CrossRef][PubMed]
    [Google Scholar]
  16. Moore DL, Causey OR, Carey DE, Reddy S, Cooke AR et al. Arthropod-borne viral infections of man in Nigeria, 1964–1970. Ann Trop Med Parasitol 1975;69:49–64 [CrossRef][PubMed]
    [Google Scholar]
  17. Beaty BJ, Jamnback TL, Hildreth SW, Brown KL. Rapid diagnosis of La Crosse virus infections: evaluation of serologic and antigen detection techniques for the clinically relevant diagnosis of La Crosse encephalitis. Prog Clin Biol Res 1983;123:293–302[PubMed]
    [Google Scholar]
  18. Clarke DH, Casals J. Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. Am J Trop Med Hyg 1958;7:561–573 [CrossRef][PubMed]
    [Google Scholar]
  19. Djikeng A, Halpin R, Kuzmickas R, Depasse J, Feldblyum J et al. Viral genome sequencing by random priming methods. BMC Genomics 2008;9:5 [CrossRef][PubMed]
    [Google Scholar]
  20. Zerbino DR, Birney E. Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res 2008;18:821–829 [CrossRef][PubMed]
    [Google Scholar]
  21. Assefa S, Keane TM, Otto TD, Newbold C, Berriman M. ABACAS: algorithm-based automatic contiguation of assembled sequences. Bioinformatics 2009;25:1968–1969 [CrossRef][PubMed]
    [Google Scholar]
  22. Edgar RC. MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res 2004;32:1792–1797 [CrossRef][PubMed]
    [Google Scholar]
  23. Gouy M, Guindon S, Gascuel O. SeaView version 4: a multiplatform graphical user interface for sequence alignment and phylogenetic tree building. Mol Biol Evol 2010;27:221–224 [CrossRef][PubMed]
    [Google Scholar]
  24. Talavera G, Castresana J. Improvement of phylogenies after removing divergent and ambiguously aligned blocks from protein sequence alignments. Syst Biol 2007;56:564–577 [CrossRef][PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/jgv.0.000899
Loading
/content/journal/jgv/10.1099/jgv.0.000899
Loading

Data & Media loading...

Supplements

Supplementary File 1

PDF

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error