RT Journal Article SR Electronic(1) A1 Hoa, Le Nguyen Minh A1 Tuan, Nguyen Anh A1 My, Pham Ha A1 Huong, Tran Thi Kieu A1 Chi, Nguyen Thi Yen A1 Hau Thu, Trang Thi A1 Carrique-Mas, Juan A1 Duong, Mai Thuy A1 Tho, Nguyen Dang A1 Hoang, Nguyen Dang A1 Thanh, To Long A1 Diep, Nguyen Thi A1 Duong, Nguyen van A1 Toan, Tran Khanh A1 Tung, Trinh Son A1 Mai, Le Quynh A1 Iqbal, Munir A1 Wertheim, Heiman A1 van Doorn, H. Rogier A1 Bryant, Juliet E. A1 the VIZIONS consortiumYR 2017 T1 Assessing evidence for avian-to-human transmission of influenza A/H9N2 virus in rural farming communities in northern Vietnam JF Journal of General Virology, VO 98 IS 8 SP 2011 OP 2016 DO https://doi.org/10.1099/jgv.0.000877 PB Microbiology Society, SN 1465-2099, AB Rural farming communities in northern Vietnam do not routinely practice vaccination for influenza A viruses (IAV) for either humans or poultry, which enables us to study transmission intensity via seroepidemiology. Using samples from a longitudinal cohort of farming households, we determined the number of symptomatic and asymptomatic human infections for seasonal IAV and avian A/H9 over 2 years. As expected, we detected virologically confirmed acute cases of seasonal IAV in humans, as well as large numbers of subclinical seroconversions to A/H1pdm [55/265 (21 %)], A/H3 [95/265 (36 %)] and A/H9 [24/265 (9 %)]. Five of the A/H9 human seroconverters likely represented true infections rather than heterosubtypic immunity, because the individuals seroconverted solely to A/H9. Among co-located poultry, we found significantly higher seroprevalance for A/H5 compared to A/H9 in both chickens and ducks [for northern study sites overall, 337/1105 (30.5 %) seropositive for A/H5 and 123/1105 (11.1 %) seropositive for A/H9]., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000877