RT Journal Article SR Electronic(1) A1 Dian, Ziqin A1 Wang, Binghui A1 Fan, Mao A1 Dong, Shuwei A1 Feng, Yue A1 Zhang, A-Mei A1 Liu, Li A1 Niu, Hua A1 Li, Yuanyue A1 Xia, XueshanYR 2017 T1 Completely genomic and evolutionary characteristics of human-dominant G9P[8] group A rotavirus strains in Yunnan, China JF Journal of General Virology, VO 98 IS 6 SP 1163 OP 1168 DO https://doi.org/10.1099/jgv.0.000807 PB Microbiology Society, SN 1465-2099, AB G9P[8] rotavirus A (RVA) has been identified as the predominant genotype circulating in Yunnan, China. To elucidate the molecular characteristics of its genetic composition at the whole-genome level, the genomes of 12 strains isolated from paediatric patients with diarrhoea were fully sequenced and characterized. Eleven of the 12 strains were genotyped as G9-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1, which is closely related to the Wa-like genotype 1 constellation. In contrast, one strain was genotyped as G9-P[8]-I1-R1-C1-M1-A1-N2-T1-E1-H1, with the NSP2 gene characterized as a DS-1 like genotype. Bayesian phylogenetic analysis indicated that G9 strains had emerged in 1932 with an estimated average evolutionary rate of 1.63×10−3 substitutions/site/year. Considering the high prevalence and fast evolutionary rate of G9P[8] rotaviruses, our results suggest that G9P[8] RVA should be strictly monitored in China., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000807