1887

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Volume 98, Issue 1

A novel alphaherpesvirus associated with fatal diseases in banded Penguins Free

Abstract

A novel avian alphaherpesvirus, preliminarily designated sphenicid alphaherpesvirus 1 (SpAHV-1), has been independently isolated from juvenile Humboldt and African penguins ( and ) kept in German zoos suffering from diphtheroid oropharyngitis/laryngotracheitis and necrotizing enteritis (collectively designated as penguin-diphtheria-like disease). High-throughput sequencing was used to determine the complete genome sequences of the first two SpAHV-1 isolates. SpAHV-1 comprises a class D genome with a length of about 164 kbp, a G+C content of 45.6 mol% and encodes 86 predicted ORFs. Taxonomic association of SpAHV-1 to the genus was supported by gene content clustering and phylogenetic analysis of herpesvirus core genes. The presented results imply that SpAHV-1 could be the primary causative agent of penguin-diphtheria-like fatal diseases in banded penguins. These results may serve as a basis for the development of diagnostic tools in order to investigate similar cases of penguin diphtheria in wild and captive penguins.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): Alphaherpesvirinae , fatal disease , high-throughput nucleotide sequencing , penguins , phylogeny and zoo animals
© 2017 The Authors
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2017-01-01
2024-04-19
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A novel alphaherpesvirus associated with fatal diseases in banded Penguins
J. Gen. Virol. 98, 89 (2017); https://doi.org/10.1099/jgv.0.000698
/content/journal/jgv/10.1099/jgv.0.000698
/content/journal/jgv/10.1099/jgv.0.000698
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