%0 Journal Article %A Blackard, Jason T. %A Ma, Gang %A Polen, Clarissa %A DuBois, Juwen C. %A Gast, Jonathon %A Radens, Caleb M. %A Sterling, Richard K. %A Sherman, Kenneth E. %T Recombination among GB virus C (GBV-C) isolates in the United States %D 2016 %J Journal of General Virology, %V 97 %N 7 %P 1537-1544 %@ 1465-2099 %R https://doi.org/10.1099/jgv.0.000477 %K genotype %K complete genome %K full-length %K recombination %K diversity %K GB virus C (GBV-C) %I Microbiology Society, %X GB virus C (GBV-C) is a non-pathogenic flavivirus that may play a role in modulating HIV disease. Multiple genotypes of GBV-C that have been identified to date that may differentially regulate HIV; however, the number of complete GBV-C sequences published to date is very limited. We sequenced full-length GBV-C genomes from four individuals with HIV/HCV co-infection in the United States. Intergenotypic recombination was evident in two of these individuals. Evaluation of additional full-length GBV-C genomes would facilitate the creation of full-length, replication-competent molecular clones of GBV-C to evaluate the phenotypic diversity of GBV-C genotypes and provide important molecular data on this understudied virus. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000477