1887

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Volume 97, Issue 7

Recombination among GB virus C (GBV-C) isolates in the United States Free

Abstract

GB virus C (GBV-C) is a non-pathogenic flavivirus that may play a role in modulating HIV disease. Multiple genotypes of GBV-C that have been identified to date that may differentially regulate HIV; however, the number of complete GBV-C sequences published to date is very limited. We sequenced full-length GBV-C genomes from four individuals with HIV/HCV co-infection in the United States. Intergenotypic recombination was evident in two of these individuals. Evaluation of additional full-length GBV-C genomes would facilitate the creation of full-length, replication-competent molecular clones of GBV-C to evaluate the phenotypic diversity of GBV-C genotypes and provide important molecular data on this understudied virus.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): complete genome , diversity , full-length , GB virus C (GBV-C) , genotype and recombination
© 2016 The Authors
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2016-07-01
2024-04-24
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Recombination among GB virus C (GBV-C) isolates in the United States
J. Gen. Virol. 97, 1537 (2016); https://doi.org/10.1099/jgv.0.000477
/content/journal/jgv/10.1099/jgv.0.000477
/content/journal/jgv/10.1099/jgv.0.000477
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