1887

Abstract

We describe a novel papillomavirus – papillomavirus 1 (RalPV1) – which causes endemic fibropapillomatosis in the European conservation breeding population of the highly endangered Visayan spotted deer (). Degenerated papillomavirus-specific primers were used to amplify and sequence parts of the viral DNA. Subsequently, the complete genomic DNA was cloned and the sequence was determined. The RalPV1 genome has a length of 8029 bp, encodes the early proteins E6, E7, E1, E2 and E5, the two late proteins L1 and L2 and contains an upstream regulatory region. Highest sequence identities were observed with two deltapapillomaviruses, the PV1 and PV1. Pairwise comparisons and phylogenetic analysis based on the ORF L1 suggested that RalPV1 is a putative new type of the papillomavirus species 5.

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2016-01-01
2019-10-21
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