RT Journal Article SR Electronic(1) A1 Arnold, Pieter A. A1 White, Craig R. A1 Johnson, Karyn N.YR 2015 T1 Drosophila melanogaster does not exhibit a behavioural fever response when infected with Drosophila C virus JF Journal of General Virology, VO 96 IS 12 SP 3667 OP 3671 DO https://doi.org/10.1099/jgv.0.000296 PB Microbiology Society, SN 1465-2099, AB Behavioural fever is a widely conserved response to infection. The host increases body temperature (T b) by altering their preferred temperature (T p), generating a fever and delaying or avoiding pathogen-induced mortality. This response is not ubiquitous in insects, however, although few studies have investigated this response to viral infection. Here, we examined the change in T p of Drosophila in response to virus infection using a thermal gradient. No difference in T p was observed. We suggest that the lack of behavioural fever could be due to the increased energy cost of maintaining a higher T b whilst the immune response is active. To the best of our knowledge, this is the first study to assay for changes in T p of infected Drosophila., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/jgv.0.000296