1887

Abstract

A herpesvirus causing a cytopathic effect was isolated from pulmonary fibroblast cultures established from a European badger (). A study was undertaken to classify and to assess some growth characteristics of this virus. From a panel of 27 mammalian cell lines, replication of the badger herpesvirus (BadHV) was only demonstrated with a mink lung cell line, suggesting a high degree of host specificity. Using PCR with degenerate primers, three independent fragments of the BadHV genome were sequenced. The largest of these fragments comprised a 6·2 kb segment including the and genes. Phylogenetic analysis of these sequences demonstrated that the BadHV is novel and clearly grouped with members of the . In view of the oncogenic and immunosuppressive potential of many related herpesviruses, it is possible that BadHV can impact on existing acute or chronic disease in badgers.

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2002-06-01
2019-12-08
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