RT Journal Article SR Electronic(1) A1 Ma, Hsin-Chieh A1 Ke, Cheng-Hung A1 Hsieh, Tsai-Yuan A1 Lo, Shih-YenYR 2002 T1 The first hydrophobic domain of the hepatitis C virus E1 protein is important for interaction with the capsid protein JF Journal of General Virology, VO 83 IS 12 SP 3085 OP 3092 DO https://doi.org/10.1099/0022-1317-83-12-3085 PB Microbiology Society, SN 1465-2099, AB The interaction between the hepatitis C virus capsid protein and the envelope protein E1 has been demonstrated previously in vivo. To determine the binding region of the E1 protein with the capsid protein, this interaction was characterized in vitro. This study shows that the interaction between these proteins should occur in the endoplasmic reticulum membrane rather than in the cytosol and that the first hydrophobic domain of the E1 protein (aa 261–291) is important for the interaction with the capsid protein., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-83-12-3085