RT Journal Article SR Electronic(1) A1 Sonoda, Satomi A1 Kitahara, Mitsuo A1 Nakayama, TetsuoYR 2002 T1 Detection of measles virus genome in bone-marrow aspirates from adults JF Journal of General Virology, VO 83 IS 10 SP 2485 OP 2488 DO https://doi.org/10.1099/0022-1317-83-10-2485 PB Microbiology Society, SN 1465-2099, AB We investigated the presence of the measles virus genome in order to identify asymptomatic infections in the adult population. Bone-marrow aspirates were obtained from 179 patients, 20–96 years of age, for the diagnosis of malignant diseases (29 with malignant lymphoma, 28 with acute leukaemia, 21 with myelodysplastic syndrome, five with multiple myeloma and 96 with other diseases). The measles virus genome was detected in 17 (9·5%) of 179 individuals by RT–PCR and 28 (15·6%) through hybridization. The genomes detected in bone marrow were all in the same cluster, D5, the strain circulating during the study period, and no evidence of persistent infection was obtained. We conclude that asymptomatic infections of measles virus are common in adults and the presence of the measles virus genome would not be related to the pathogenesis of illness., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-83-10-2485