1887

Abstract

Phylogenetic analyses of the envelope (E) gene sequence of five recently isolated dengue virus type 4 (DENV-4) suggested the emergence of a distinct geographical and temporal DENV-4 subgenotype IIA in Malaysia. Four of the isolates had direct ancestral lineage with DENV-4 Indonesia 1973 and showed evidence of intra-serotypic recombination with the other recently isolated DENV-4, MY01-22713. The E gene of isolate MY01-22713 had strong evidence of an earlier recombination involving DENV-4 genotype II Indonesia 1976 and genotype I Malaysia 1969. These results suggest that intra-serotypic recombination amongst DENV-4 from independent ancestral lineages may have contributed to the emergence of DENV-4 subgenotype IIA in Malaysia.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-83-10-2437
2002-10-01
2021-01-22
Loading full text...

Full text loading...

/deliver/fulltext/jgv/83/10/0832437a.html?itemId=/content/journal/jgv/10.1099/0022-1317-83-10-2437&mimeType=html&fmt=ahah

References

  1. Lanciotti R. S., Gubler D. J., Trent D. W. 1997; Molecular evolution and phylogeny of dengue-4 viruses. Journal of General Virology 78:2279–2286
    [Google Scholar]
  2. Lole K. S., Bollinger R. C., Paranjape R. S., Gadkari D., Kulkarni S. S., Novak N. G., Ingersoll R., Sheppard H. W., Ray S. C. 1999; Full-length human immunodeficiency virus type 1 genomes from subtype C-infected seroconverters in India, with evidence of intersubtype recombination. Journal of Virology 73:152–160
    [Google Scholar]
  3. Nicholas K. B., Nicholas H. B. Jr 1997; Genedoc: a tool for editing and annotating multiple sequence alignments. http://www.cris.com/∼ketchup/genedoc.shtml
  4. Page R. D. 1996; treeview: an application to display phylogenetic trees on personal computers. Computer Applications in the Biosciences 12:357–358
    [Google Scholar]
  5. Rudnick A. 1984; The ecology of the dengue virus complex in peninsular Malaysia. In Proceedings of the International Conference on Dengue/DHF pp 7 Edited by Pang T., Padmanathan R. Kuala Lumpur: University of Malaysia Press;
    [Google Scholar]
  6. Rudnick A. 1986; Dengue fever epidemiology in Malaysia 1901–1980. In Dengue Fever Studies in Malaysia, Bulletin No 23 pp 9–38 Edited by Rudnick A., Lim T. W. Kuala Lumpur: Institute of Medical Research;
    [Google Scholar]
  7. Saitou N., Nei M. 1987; The neighbor-joining method: a new method for reconstructing phylogenetic trees. Molecular Biology and Evolution 4:406–425
    [Google Scholar]
  8. Salminen M. O., Carr J. K., Burke D. S., McCutchan F. E. 1995; Identification of breakpoints in intergenotypic recombinants of HIV type 1 by bootscanning. AIDS Research and Human Retroviruses 11:1423–1425
    [Google Scholar]
  9. Seah C. L., Chow V. T., Tan H. C., Chan Y. C. 1995; Rapid, single-step RT–PCR typing of dengue viruses using five NS3 gene primers. Journal of Virological Methods 51:193–200
    [Google Scholar]
  10. Thompson J. D., Gibson T. J., Plewniak F., Jeanmougin F., Higgins D. G. 1997; The clustal x windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Research 24:4876–4882
    [Google Scholar]
  11. Tolou H. J., Couissinier-Paris P., Durand J.-P., Mercier V., de Pina J.-J., de Micco P., Billoir F., Charrel R. N., de Lamballerie X. 2001; Evidence for recombination in natural populations of dengue virus type 1 based on the analysis of complete genome sequences. Journal of General Virology 82:1283–1290
    [Google Scholar]
  12. Uzcategui N. Y., Camacho D., Comach G., Cuello de Uzcategui R., Holmes E. C., Gould E. A. 2001; Molecular epidemiology of dengue type 2 virus in Venezuela: evidence for in situ virus evolution and recombination. Journal of General Virology 82:2945–2953
    [Google Scholar]
  13. Wang E., Ni H., Xu R., Barrett A. D., Watowich S. J., Gubler D. J., Weaver S. C. 2000; Evolutionary relationships of the endemic/epidemic and sylvatic dengue viruses. Journal of Virology 74:3227–3234
    [Google Scholar]
  14. WHO 1998; Dengue and dengue hemorrhagic fever. WHO Fact Sheet 117: http://www.who.int/inf-fs/en/fact117.html
    [Google Scholar]
  15. WHO 2000; Report on global surveillance of epidemic-prone infection disease. http://www.who.int/emc-documents/surveillance/docs/whocdscsnisr2001.html/dengue/TabDFAsia.htm
  16. Worobey M., Holmes E. C. 1999; Evolutionary aspects of recombination in RNA viruses. Journal of General Virology 80:2535–2543
    [Google Scholar]
  17. Worobey M., Rambaut A., Holmes E. C. 1999; Widespread intra-serotype recombination in natural populations of dengue virus. Proceedings of the National Academy of Sciences, USA 96:7352–7357
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-83-10-2437
Loading
/content/journal/jgv/10.1099/0022-1317-83-10-2437
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error