A haemagglutinin (HA1)-specific FAb neutralizes influenza A virus by inhibiting fusion activity

References

1. Caton A. J., Brownlee G. G., Yewdell J. W., Gerhard W. 1982; The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype. Cell 31:417–427
   [Google Scholar]
2. Daukas G., Zigmond S. H. 1985; Inhibition of receptor-mediated but not fluid-phase endocytosis in polymorphonuclear leukocytes. Journal of Cell Biology 101:1673–1679
   [Google Scholar]
3. Dimmock N. J. 1993; Neutralization of animal viruses. Current Topics in Microbiology and Immunology 183:1–149
   [Google Scholar]
4. Dimmock N. J. 1995; Update on the neutralisation of animal viruses. Reviews in Medical Virology 5:165–179
   [Google Scholar]
5. Doms R. W. 1993; Protein conformational changes in virus–cell fusion. Methods in Enzymology 221:61–72
   [Google Scholar]
6. Edwards M. J., Dimmock N. J. 2000; Two influenza A virus-specific Fabs neutralize by inhibiting virus attachment to target cells, while neutralization by their IgGs is complex and occurs simultaneously through fusion inhibition and attachment inhibition. Virology 278:423–435
   [Google Scholar]
7. Fleury D., Barrere B., Bizebard T., Daniels R. S., Skehel J. J., Knossow M. 1999; A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site. Nature Structural Biology 6:530–534
   [Google Scholar]
8. Gaudin Y., Ruigrok R. W. H., Brunner J. 1995; Low-pH induced conformational changes in viral fusion proteins: implications for the fusion mechanism. Journal of General Virology 76:1541–1556
   [Google Scholar]
9. Ghendon Y. 1990; The immune response to influenza vaccines. Acta Virologica 34:295–304
   [Google Scholar]
10. Guinea R., Carrasco L. 1995; Requirement for vacuolar proton-ATPase activity during entry of influenza virus into cells. Journal of Virology 69:2306–2312
    [Google Scholar]
11. Heuser J. E., Anderson R. G. W. 1989; Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. Journal of Cell Biology 108:389–400
    [Google Scholar]
12. Hörling J., Lundkvist A., Huggins J. W., Niklasson B. 1992; Antibodies to Puumala virus in humans determined by neutralization test. Journal of Virological Methods 39:139–147
    [Google Scholar]
13. Matlin K. S., Reggio H., Helenius A., Simons K. 1981; Infectious entry pathway of influenza virus in a canine kidney cell line. Journal of Cell Biology 91:601–613
    [Google Scholar]
14. Ochiai H., Sakai S., Hirabayashi T., Shimizu Y., Terasawa K. 1995; Inhibitory effect of bafilomycin A1, a specific inhibitor of vacuolar-type proton pump, on the growth of influenza A and B viruses in MDCK cells. Antiviral Research 27:425–430
    [Google Scholar]
15. Palokangas H., Metsikkö K., Väänänen K. 1994; Active vacuolar H⁺ATPase is required for both endocytic and exocytic processes during viral infection of BHK-21 cells. Journal of Biological Chemistry 269:17577–17585
    [Google Scholar]
16. Puri A., Booy F. P., Doms R. W., White J. M., Blumenthal R. 1990; Conformational changes and fusion activity of influenza virus hemagglutinin of the H2 and H3 subtypes: effects of acid pretreatment. Journal of Virology 64:3824–3832
    [Google Scholar]
17. Richman D. D., Hostetler K. Y., Yazaki P. J., Clark S. 1986; Fate of influenza A virion proteins after entry into subcellular fractions of LLC cells and the effect of amantadine. Virology 151:200–210
    [Google Scholar]
18. Schofield D. J., Dimmock N. J. 1996; Determination of affinities of a panel of IgGs and Fabs for whole enveloped (influenza A) virions using surface plasmon resonance. Journal of Virological Methods 62:33–42
    [Google Scholar]
19. Schofield D. J., Stephenson J. R., Dimmock N. J. 1997a; Variations in the neutralizing and haemagglutination-inhibiting activities of five influenza A virus-specific IgGs and their antibody fragments. Journal of General Virology 78:2431–2439
    [Google Scholar]
20. Schofield D. J., Stephenson J. R., Dimmock N. J. 1997b; High and low efficiency neutralization epitopes on the haemagglutinin of type A influenza virus. Journal of General Virology 78:2441–2446
    [Google Scholar]
21. Staudt L. M., Gerhard W. 1983; Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. I. Significant variation in repertoire expression between individual mice. Journal of Experimental Medicine 157:687–704
    [Google Scholar]
22. Stegmann T., Helenius A. 1993; Influenza virus fusion: from models towards a mechanism. In Viral Fusion Mechanism pp 89–111 Edited by Bentz J. Boca Raton, FL: CRC Press;
    [Google Scholar]
23. Stegmann T., White J. M., Helenius A. 1990; Intermediates in influenza induced membrane fusion. EMBO Journal 9:4231–4241
    [Google Scholar]
24. Wiley D. C., Wilson I. A., Skehel J. J. 1981; Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation. Nature 289:373–378
    [Google Scholar]
25. Wilson I. A., Stanfield R. L. 1993; Antibody–antigen interactions. Current Opinion in Structural Biology 3:113–118
    [Google Scholar]