1887

Abstract

A serological survey for human T-lymphotropic virus (HTLV)/simian T-lymphotropic virus (STLV) antibodies was performed in 102 wild-caught monkeys and apes from 15 (sub)species originating from Cameroon. Two animals (a and a ) exhibited a complete HTLV-1 seroreactivity pattern while two others lacked either the p24 (a ) or the MTA-1/gp46 bands (a ). Sequence comparison and phylogenetic analyses, using a 522 bp gene fragment and the complete LTR, indicated that the two mandrill STLV strains belonged to the HTLV/STLV subtype D clade while the chimpanzee strain clustered in the HTLV/STLV subtype B clade. The STLV strain, the first one found in this species, was closely related to the two HTLV/STLV subtype F strains. Such data indicate that the African biodiversity of STLV-1 in the wild is far from being known and reinforces the hypothesis of interspecies transmission of STLV-1 from monkeys and apes to humans leading to the present day distribution of HTLV-1 in African inhabitants.

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2001-12-01
2019-10-20
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References

  1. Durand, J. P., Tuppin, P., Maison, P., Galat, G., Galat-Luong, A., Jeannel, D. & De The, G. ( 1995; ). Increased risk for a second retroviral infection (SIV or STLV type I) for wild African green monkeys already infected by one retrovirus in Senegal (West Africa). AIDS Research and Human Retroviruses 11, 985-988.[CrossRef]
    [Google Scholar]
  2. Englebrecht, S., van Rensburg, E. J. & Robson, B. A. ( 1996; ). Sequence variation and subtyping of human and simian T-cell lymphotropic virus type I strains from South Africa. Journal of Acquired Immune Deficiency Syndrome and Human Retrovirology 12, 298-302.[CrossRef]
    [Google Scholar]
  3. Gessain, A., Gallo, R. C. & Franchini, G. ( 1992; ). Low degree of human T-cell leukemia/lymphoma virus type I genetic drift in vivo as a means of monitoring viral transmission and movement of ancient human populations. Journal of Virology 66, 2288-2295.
    [Google Scholar]
  4. Guo, H. G., Wong-Stall, F. & Gallo, R. C. ( 1984; ). Novel viral sequences related to human T-cell leukemia virus in T cells of a seropositive baboon. Science 223, 1195-1197.[CrossRef]
    [Google Scholar]
  5. Ibrahim, F., de The, G. & Gessain, A. ( 1995; ). Isolation and characterization of a new simian T-cell leukemia virus type 1 from naturally infected Celebes macaques (Macaca tonkeana): complete nucleotide sequence and phylogenetic relationship with the Australo–Melanesian human T-cell leukemia virus type 1. Journal of Virology 69, 6980-6993.
    [Google Scholar]
  6. Ishikawa, K., Fukasawa, M., Tsujimoto, H., Else, J. G., Isahakia, M., Ubhi, N. K., Ishida, T., Takenaka, O., Kawamoto, Y., Shotake, T. and others ( 1987; ). Serological survey and virus isolation of simian T-cell leukemia/T-lymphotropic virus type I (STLV-I) in non-human primates in their native countries. International Journal of Cancer 40, 233–239.[CrossRef]
    [Google Scholar]
  7. Koralnik, I. J., Boeri, E., Saxinger, W. C., Monico, A. L., Fullen, J., Gessain, A., Guo, H. G., Gallo, R. C., Markham, P., Kalyanaraman, V. and others ( 1994; ). Phylogenetic associations of human and simian T-cell leukemia/lymphotropic virus type I strains: evidence for interspecies transmission. Journal of Virology 68, 2693–2707.
    [Google Scholar]
  8. Mahieux, R., Ibrahim, F., Mauclere, P., Herve, V., Michel, P., Tekaia, F., Chappey, C., Garin, B., Van Der Ryst, E., Guillemain, B., Ledru, E., Delaporte, E., de The, G. & Gessain, A. ( 1997; ). Molecular epidemiology of 58 new African human T-cell leukemia virus type 1 (HTLV-1) strains: identification of a new and distinct HTLV-1 molecular subtype in Central Africa and in Pygmies. Journal of Virology 71, 1317-1333.
    [Google Scholar]
  9. Mahieux, R., Chappey, C., Georges-Courbot, M. C., Dubreuil, G., Mauclere, P., Georges, A. & Gessain, A. ( 1998a; ). Simian T-cell lymphotropic virus type 1 from Mandrillus sphinx as a simian counterpart of human T-cell lymphotropic virus type 1 subtype D. Journal of Virology 72, 10316-10322.
    [Google Scholar]
  10. Mahieux, R., Pecon-Slattery, J., Chen, G. M. & Gessain, A. ( 1998b; ). Evolutionary inferences of novel simian T lymphotropic virus type 1 from wild-caught chacma (Papio ursinus) and olive baboons (Papio anubis). Virology 251, 71-84.[CrossRef]
    [Google Scholar]
  11. Mahieux, R., Chappey, C., Meertens, L., Mauclere, P., Lewis, J. & Gessain, A. ( 2000; ). Molecular characterization and phylogenetic analyses of a new simian T cell lymphotropic Virus type 1 in a wild-caught African baboon (Papio anubis) with an indeterminate STLV type 2-like serology. AIDS Research and Human Retroviruses 16, 2043-2048.[CrossRef]
    [Google Scholar]
  12. Miyoshi, I., Yoshimoto, S., Fujishita, M., Taguchi, H., Kubonishi, I., Niiya, K. & Minezawa, M. (1982). Natural adult T-cell leukemia virus infection in Japanese monkeys [letter]. Lancet ii, 658.
  13. Nerrienet, E., Amouretti, X., Muller-Trutwin, M. C., Poaty-Mavoungou, V., Bedjebaga, I., Nguyen, H. T., Dubreuil, G., Corbet, S., Wickings, E. J., Barre-Sinoussi, F., Georges, A. J. & Georges-Courbot, M. C. ( 1998; ). Phylogenetic analysis of SIV and STLV type I in mandrills (Mandrillus sphinx): indications that intracolony transmissions are predominantly the result of male-to-male aggressive contacts. AIDS Research and Human Retroviruses 14, 785-796.[CrossRef]
    [Google Scholar]
  14. Saksena, N. K., Herve, V., Sherman, M. P., Durand, J. P., Mathiot, C., Muller, M., Love, J. L., LeGuenno, B., Sinoussi, F. B., Dube, D. K. and others ( 1993; ). Sequence and phylogenetic analyses of a new STLV-I from a naturally infected tantalus monkey from Central Africa. Virology 192, 312–320.[CrossRef]
    [Google Scholar]
  15. Saksena, N. K., Herve, V., Durand, J. P., Leguenno, B., Diop, O. M., Digouette, J. P., Mathiot, C., Muller, M. C., Love, J. L., Dube, S. and others ( 1994; ). Seroepidemiologic, molecular, and phylogenetic analyses of simian T-cell leukemia viruses (STLV-I) from various naturally infected monkey species from central and western Africa. Virology 198, 297–310.[CrossRef]
    [Google Scholar]
  16. Salemi, M., Desmyter, J. & Vandamme, A. M. ( 2000; ). Tempo and mode of human and simian T-lymphotropic virus (HTLV/STLV) evolution revealed by analyses of full-genome sequences. Molecular Biology and Evolution 17, 374-386.[CrossRef]
    [Google Scholar]
  17. Slattery, J. P., Franchini, G. & Gessain, A. ( 1999; ). Genomic evolution, patterns of global dissemination, and interspecies transmission of human and simian T-cell leukemia/lymphotropic viruses. Genome Research 9, 525-540.
    [Google Scholar]
  18. Van Dooren, S., Salemi, M. & Vandamme, A. M. ( 2001; ). Dating the origin of the African human T-cell lymphotropic virus type-I (HTLV-I) subtypes. Molecular Biology and Evolution 18, 661-671.[CrossRef]
    [Google Scholar]
  19. van Rensburg, E., Engelbrecht, S., Robson, B., Langat, D., Isahakia, M. & Mwenda, J. ( 1999; ). Phylogenetic analysis of simian T lymphotropic virus type I from Kenyan olive baboons (Papio anubis), lowland Sykes monkeys (Cercopithecus mitis), and vervet monkeys (Cercopithecus aethiops pygerythrus). AIDS Research and Human Retroviruses 15, 781-784.[CrossRef]
    [Google Scholar]
  20. Voevodin, A., Miura, T., Samilchuk, E. & Schatzl, H. ( 1996a; ). Phylogenetic characterization of simian T lymphotropic virus type I (STLV-I) from the Ethiopian sacred baboon (Papio hamadryas). AIDS Research and Human Retroviruses 12, 255-258.[CrossRef]
    [Google Scholar]
  21. Voevodin, A., Samilchuk, E., Schatzl, H., Boeri, E. & Franchini, G. ( 1996b; ). Interspecies transmission of macaque simian T-cell leukemia/lymphoma virus type 1 in baboons resulted in an outbreak of malignant lymphoma. Journal of Virology 70, 1633-1639.
    [Google Scholar]
  22. Voevodin, A., Samilchuk, E., Allan, J., Rogers, J. & Broussard, S. ( 1997a; ). Simian T-lymphotropic virus type 1 (STLV-1) infection in wild yellow baboons (Papio hamadryas cynocephalus) from Mikumi National Park, Tanzania. Virology 228, 350-359.[CrossRef]
    [Google Scholar]
  23. Voevodin, A. F., Johnson, B. K., Samilchuk, E. I., Stone, G. A., Druilhet, R., Greer, W. J. & Gibbs, C. J.Jr ( 1997b; ). Phylogenetic analysis of simian T-lymphotropic virus type I (STLV-I) in common chimpanzees (Pan troglodytes): evidence for interspecies transmission of the virus between chimpanzees and humans in Central Africa. Virology 238, 212-220.[CrossRef]
    [Google Scholar]
  24. Watanabe, T., Seiki, M., Tsujimoto, H., Miyoshi, I., Hayami, M. & Yoshida, M. ( 1985; ). Sequence homology of the simian retrovirus genome with human T-cell leukemia virus type I. Virology 144, 59-65.[CrossRef]
    [Google Scholar]
  25. Watanabe, T., Seiki, M., Hirayama, Y. & Yoshida, M. ( 1986; ). Human T-cell leukemia virus type I is a member of the African subtype of simian viruses (STLV). Virology 148, 385-388.[CrossRef]
    [Google Scholar]
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