1887

Abstract

A serological survey for human T-lymphotropic virus (HTLV)/simian T-lymphotropic virus (STLV) antibodies was performed in 102 wild-caught monkeys and apes from 15 (sub)species originating from Cameroon. Two animals (a and a ) exhibited a complete HTLV-1 seroreactivity pattern while two others lacked either the p24 (a ) or the MTA-1/gp46 bands (a ). Sequence comparison and phylogenetic analyses, using a 522 bp gene fragment and the complete LTR, indicated that the two mandrill STLV strains belonged to the HTLV/STLV subtype D clade while the chimpanzee strain clustered in the HTLV/STLV subtype B clade. The STLV strain, the first one found in this species, was closely related to the two HTLV/STLV subtype F strains. Such data indicate that the African biodiversity of STLV-1 in the wild is far from being known and reinforces the hypothesis of interspecies transmission of STLV-1 from monkeys and apes to humans leading to the present day distribution of HTLV-1 in African inhabitants.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-82-12-2973
2001-12-01
2020-08-12
Loading full text...

Full text loading...

/deliver/fulltext/jgv/82/12/0822973a.html?itemId=/content/journal/jgv/10.1099/0022-1317-82-12-2973&mimeType=html&fmt=ahah

References

  1. Durand J. P., Tuppin P., Maison P., Galat G., Galat-Luong A., Jeannel D., De The G.. 1995; Increased risk for a second retroviral infection (SIV or STLV type I) for wild African green monkeys already infected by one retrovirus in Senegal (West Africa). AIDS Research and Human Retroviruses11:985–988
    [Google Scholar]
  2. Englebrecht S., van Rensburg E. J., Robson B. A.. 1996; Sequence variation and subtyping of human and simian T-cell lymphotropic virus type I strains from South Africa. Journal of Acquired Immune Deficiency Syndrome and Human Retrovirology12:298–302
    [Google Scholar]
  3. Gessain A., Gallo R. C., Franchini G.. 1992; Low degree of human T-cell leukemia/lymphoma virus type I genetic drift in vivo as a means of monitoring viral transmission and movement of ancient human populations. Journal of Virology66:2288–2295
    [Google Scholar]
  4. Guo H. G., Wong-Stall F., Gallo R. C.. 1984; Novel viral sequences related to human T-cell leukemia virus in T cells of a seropositive baboon. Science223:1195–1197
    [Google Scholar]
  5. Ibrahim F., de The G., Gessain A.. 1995; Isolation and characterization of a new simian T-cell leukemia virus type 1 from naturally infected Celebes macaques ( Macaca tonkeana ): complete nucleotide sequence and phylogenetic relationship with the Australo–Melanesian human T-cell leukemia virus type 1. Journal of Virology69:6980–6993
    [Google Scholar]
  6. Ishikawa K., Fukasawa M., Tsujimoto H., Else J. G., Isahakia M., Ubhi N. K., Ishida T., Takenaka O., Kawamoto Y., Shotake T.. and others 1987; Serological survey and virus isolation of simian T-cell leukemia/T-lymphotropic virus type I (STLV-I) in non-human primates in their native countries. International Journal of Cancer40:233–239
    [Google Scholar]
  7. Koralnik I. J., Boeri E., Saxinger W. C., Monico A. L., Fullen J., Gessain A., Guo H. G., Gallo R. C., Markham P., Kalyanaraman V.. and others 1994; Phylogenetic associations of human and simian T-cell leukemia/lymphotropic virus type I strains: evidence for interspecies transmission. Journal of Virology68:2693–2707
    [Google Scholar]
  8. Mahieux R., Ibrahim F., Mauclere P., Herve V., Michel P., Tekaia F., Chappey C., Garin B., Van Der Ryst E., Guillemain B., Ledru E., Delaporte E., de The G., Gessain A.. 1997; Molecular epidemiology of 58 new African human T-cell leukemia virus type 1 (HTLV-1) strains: identification of a new and distinct HTLV-1 molecular subtype in Central Africa and in Pygmies. Journal of Virology71:1317–1333
    [Google Scholar]
  9. Mahieux R., Chappey C., Georges-Courbot M. C., Dubreuil G., Mauclere P., Georges A., Gessain A.. 1998a; Simian T-cell lymphotropic virus type 1 from Mandrillus sphinx as a simian counterpart of human T-cell lymphotropic virus type 1 subtype D. Journal of Virology72:10316–10322
    [Google Scholar]
  10. Mahieux R., Pecon-Slattery J., Chen G. M., Gessain A.. 1998b; Evolutionary inferences of novel simian T lymphotropic virus type 1 from wild-caught chacma ( Papio ursinus ) and olive baboons ( Papio anubis ). Virology251:71–84
    [Google Scholar]
  11. Mahieux R., Chappey C., Meertens L., Mauclere P., Lewis J., Gessain A.. 2000; Molecular characterization and phylogenetic analyses of a new simian T cell lymphotropic Virus type 1 in a wild-caught African baboon ( Papio anubis ) with an indeterminate STLV type 2-like serology. AIDS Research and Human Retroviruses16:2043–2048
    [Google Scholar]
  12. Miyoshi I., Yoshimoto S., Fujishita M., Taguchi H., Kubonishi I., Niiya K., Minezawa M.. 1982; Natural adult T-cell leukemia virus infection in Japanese monkeys [letter]. Lancetii:658
    [Google Scholar]
  13. Nerrienet E., Amouretti X., Muller-Trutwin M. C., Poaty-Mavoungou V., Bedjebaga I., Nguyen H. T., Dubreuil G., Corbet S., Wickings E. J., Barre-Sinoussi F., Georges A. J., Georges-Courbot M. C.. 1998; Phylogenetic analysis of SIV and STLV type I in mandrills ( Mandrillus sphinx ): indications that intracolony transmissions are predominantly the result of male-to-male aggressive contacts. AIDS Research and Human Retroviruses14:785–796
    [Google Scholar]
  14. Saksena N. K., Herve V., Sherman M. P., Durand J. P., Mathiot C., Muller M., Love J. L., LeGuenno B., Sinoussi F. B., Dube D. K.. and others 1993; Sequence and phylogenetic analyses of a new STLV-I from a naturally infected tantalus monkey from Central Africa. Virology192:312–320
    [Google Scholar]
  15. Saksena N. K., Herve V., Durand J. P., Leguenno B., Diop O. M., Digouette J. P., Mathiot C., Muller M. C., Love J. L., Dube S.. and others 1994; Seroepidemiologic, molecular, and phylogenetic analyses of simian T-cell leukemia viruses (STLV-I) from various naturally infected monkey species from central and western Africa. Virology198:297–310
    [Google Scholar]
  16. Salemi M., Desmyter J., Vandamme A. M.. 2000; Tempo and mode of human and simian T-lymphotropic virus (HTLV/STLV) evolution revealed by analyses of full-genome sequences. Molecular Biology and Evolution17:374–386
    [Google Scholar]
  17. Slattery J. P., Franchini G., Gessain A.. 1999; Genomic evolution, patterns of global dissemination, and interspecies transmission of human and simian T-cell leukemia/lymphotropic viruses. Genome Research9:525–540
    [Google Scholar]
  18. Van Dooren S., Salemi M., Vandamme A. M.. 2001; Dating the origin of the African human T-cell lymphotropic virus type-I (HTLV-I) subtypes. Molecular Biology and Evolution18:661–671
    [Google Scholar]
  19. van Rensburg E., Engelbrecht S., Robson B., Langat D., Isahakia M., Mwenda J.. 1999; Phylogenetic analysis of simian T lymphotropic virus type I from Kenyan olive baboons ( Papio anubis ), lowland Sykes monkeys ( Cercopithecus mitis ), and vervet monkeys ( Cercopithecus aethiops pygerythrus ). AIDS Research and Human Retroviruses15:781–784
    [Google Scholar]
  20. Voevodin A., Miura T., Samilchuk E., Schatzl H.. 1996a; Phylogenetic characterization of simian T lymphotropic virus type I (STLV-I) from the Ethiopian sacred baboon ( Papio hamadryas ). AIDS Research and Human Retroviruses12:255–258
    [Google Scholar]
  21. Voevodin A., Samilchuk E., Schatzl H., Boeri E., Franchini G.. 1996b; Interspecies transmission of macaque simian T-cell leukemia/lymphoma virus type 1 in baboons resulted in an outbreak of malignant lymphoma. Journal of Virology70:1633–1639
    [Google Scholar]
  22. Voevodin A., Samilchuk E., Allan J., Rogers J., Broussard S.. 1997a; Simian T-lymphotropic virus type 1 (STLV-1) infection in wild yellow baboons ( Papio hamadryas cynocephalus ) from Mikumi National Park, Tanzania. Virology228:350–359
    [Google Scholar]
  23. Voevodin A. F., Johnson B. K., Samilchuk E. I., Stone G. A., Druilhet R., Greer W. J., Gibbs C.J. Jr. 1997b; Phylogenetic analysis of simian T-lymphotropic virus type I (STLV-I) in common chimpanzees ( Pan troglodytes ): evidence for interspecies transmission of the virus between chimpanzees and humans in Central Africa. Virology238:212–220
    [Google Scholar]
  24. Watanabe T., Seiki M., Tsujimoto H., Miyoshi I., Hayami M., Yoshida M.. 1985; Sequence homology of the simian retrovirus genome with human T-cell leukemia virus type I. Virology144:59–65
    [Google Scholar]
  25. Watanabe T., Seiki M., Hirayama Y., Yoshida M.. 1986; Human T-cell leukemia virus type I is a member of the African subtype of simian viruses (STLV. Virology148:385–388
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-82-12-2973
Loading
/content/journal/jgv/10.1099/0022-1317-82-12-2973
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error