1887

Abstract

The circular, single-stranded DNA genome of a novel circovirus of canaries, tentatively named canary circovirus (CaCV), was cloned and sequenced. Sequence analysis indicated that the genome was 1952 nucleotides (nt) in size and had the potential to encode three viral proteins, including the putative capsid and replication-associated (Rep) proteins. The CaCV genome shared greatest sequence similarity (58·3% nt identity) with the newly characterized columbid circovirus (CoCV) and was more distantly related to the two porcine circovirus strains, PCV1 and PCV2, beak and feather disease virus (BFDV) and a recently isolated goose circovirus (GCV) isolate (46·8–50·9% nt identity). In common with other members of the genus, several nt structures and amino acid motifs thought to be implicated in virus replication were identified on the putative viral strand. Phylogenetic analysis of both the capsid and Rep protein-coding regions provided further evidence that CaCV is more closely related to CoCV and BFDV and more distantly related to GCV, PCV1 and PCV2.

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2001-11-01
2024-04-23
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References

  1. Altschul S. F., Gish W., Miller W., Myers E. W., Lipman D. J. 1990; Basic local alignment search tool. Journal of Molecular Biology 215:403–410
    [Google Scholar]
  2. Bassami M. R., Berryman D., Wilcox G. E., Raidal S. R. 1998; Psittacine beak and feather disease virus nucleotide sequence analysis and its relationship to porcine circovirus, plant circoviruses, and chicken anaemia virus. Virology 249:453–459
    [Google Scholar]
  3. Bassami M. R., Ypelaar I., Berryman D., Wilcox G. E., Raidal S. R. 2001; Genetic diversity of beak and feather disease virus detected in psittacine species in Australia. Virology 279:392–400
    [Google Scholar]
  4. Goldsmith T. L. 1995; Documentation of passerine circoviral infection. In Proceedings of the Annual Conference of the Association of Avian Veterinarians pp 349–350 August 1995 Philadelphia, PA, USA:
    [Google Scholar]
  5. Mankertz A., Persson F., Mankertz J., Blaess G., Buhk H. J. 1997; Mapping and characterization of the origin of DNA replication of porcine circovirus. Journal of Virology 71:2562–2566
    [Google Scholar]
  6. Mankertz A., Hattermann K., Ehlers B., Soike D. 2000; Cloning and sequencing of columbid circovirus (CoCV), a new circovirus from pigeons. Archives of Virology 145:2469–2479
    [Google Scholar]
  7. Meehan B. M., Creelan J. L., McNulty M. S., Todd D. 1997; Sequence of porcine circovirus DNA: affinities with plant circoviruses. Journal of General Virology 78:221–227
    [Google Scholar]
  8. Meehan B. M., McNeilly F., Todd D., Kennedy S., Jewhurst V. A., Ellis J. A., Hassard L. E., Clark E. G., Haines D. M., Allan G. A. 1998; Characterization of novel circovirus DNAs associated with wasting syndromes in pigs. Journal of General Virology 79:2171–2179
    [Google Scholar]
  9. Niagro F. D., Forsthoefel A. N., Lawther R. P., Kamalanathan L., Ritchie B. W., Latimer K. S., Lukert P. D. 1998; Beak and feather disease virus and porcine circovirus genomes: intermediates between the geminiviruses and plant circoviruses. Archives of Virology 143:1723–1744
    [Google Scholar]
  10. Noteborn M. H., de Boer G. F., van Roozelaar D. J., Karreman C., Kranenburg O., Vos J. G., Jeurissen S. H., Hoeben R. C., Zantema A., Koch G. 1991; Characterisation of cloned chicken anemia virus DNA that contains all elements for the infectious replication cycle. Journal of Virology 65:3131–3139
    [Google Scholar]
  11. Pringle C. R. 1999; Virus taxonomy at the XIth International Congress of Virology, Sydney, Australia, 1999. Archives of Virology 144:2065–2070
    [Google Scholar]
  12. Saitou N., Nei M. 1987; The neighbor-joining method: a new method for reconstructing phylogenetic trees. Molecular Biology and Evolution 4:406–425
    [Google Scholar]
  13. Todd D. 2000; Circoviruses: immunosuppressive threats to avian species: a review. Avian Pathology 29:373–394
    [Google Scholar]
  14. Todd D., Weston J. H., Soike D., Smyth J. A. 2001a; Genome sequence determinations and analyses of novel circoviruses from goose and pigeon. Virology 286:354–362
    [Google Scholar]
  15. Todd D., Weston J. H., Ball N. W., Borghmans B. J., Smyth J. A., Gelmini L., Lavazza A. 2001b; Nucleotide sequence identification of a novel circovirus from canaries. Avian Pathology 30:321–325
    [Google Scholar]
  16. Woods L. W., Latimer K. S. 2000; Circovirus infection of nonpsittacine birds. Journal of Avian Medicine and Surgery 14:154–163
    [Google Scholar]
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