Deletion or substitution of the aphthovirus 3′ NCR abrogates infectivity and virus replication

References

1. Agol V. I., Paul A. V., Wimmer E. 1999; Paradoxes of the replication of picornaviral genomes. Virus Research 62:129–147
   [Google Scholar]
2. Alexander L., Lu H. H., Wimmer E. 1994; Polioviruses containing picornavirus type 1 and/or type 2 internal ribosomal entry site elements: genetic hybrids and the expression of a foreign gene. Proceedings of the National Academy of Sciences, USA 91:1406–1410
   [Google Scholar]
3. Bigeriego P., Rosas M. F., Zamora E., Martínez-Salas E., Sobrino F. 1999; Heterotypic inhibition of foot-and-mouth disease virus infection by combinations of RNA transcripts corresponding to the 5′ and 3′ regions. Antiviral Research 44:133–141
   [Google Scholar]
4. Chatterjee N. K., Polatnick J., Bachrach H. L. 1976; Cell-free translation of foot-and-mouth disease virus RNA into identifiable non-capsid and capsid proteins. Journal of General Virology 32:383–394
   [Google Scholar]
5. Clarke B. E., Brown A. L., Currey K. M., Newton S. E., Rowlands D. J., Carroll A. R. 1987; Potential secondary and tertiary structure in the genomic RNA of foot-and-mouth disease virus. Nucleic Acids Research 15:7067–7079
   [Google Scholar]
6. Cui T., Sankar S., Porter A. G. 1993; Binding of encephalomyocarditis virus RNA polymerase to the 3′-noncoding region of the viral RNA is specific and requires the 3′-poly(A) tail. Journal of Biological Chemistry 268:26093–26098
   [Google Scholar]
7. Falk M. M., Sobrino F., Beck E. 1992; VPg gene amplification correlates with infective particle formation in foot-and-mouth disease virus. Journal of Virology 66:2251–2260
   [Google Scholar]
8. Gamarnik A. V., Andino R. 1998; Switch from translation to RNA replication in a positive-stranded RNA virus. Genes & Development 12:2293–2304
   [Google Scholar]
9. Goodfellow I., Chaudhry Y., Richardson A., Meredith J., Almond J. W., Barclay W., Evans D. J. 2000; Identification of a cis -acting replication element within the poliovirus coding region. Journal of Virology 74:4590–4600
   [Google Scholar]
10. Gutiérrez A., Martínez-Salas E., Pintado B., Sobrino F. 1994; Specific inhibition of aphthovirus infection by RNAs transcribed from both 5′ and 3′ noncoding region. Journal of Virology 68:7426–7432
    [Google Scholar]
11. Harris K. S., Xiang W., Alexander L., Lane W. S., Paul A. V., Wimmer E. 1994; Interaction of poliovirus polypeptide 3CD^pro with the 5′ and 3′ termini of the poliovirus genome. Identification of viral and cellular co-factors needed for efficient binding. Journal of Biological Chemistry 269:27004–27014
    [Google Scholar]
12. Herold J., Andino R. 2000a; Functional circularization of a positive-stranded RNA virus: a new model for the initiation of negative strand RNA synthesis in poliovirus replication. Europic 2000 (Zagare Bay, Gargano, Italy, 25–31 May 2000). Abstract G09
    [Google Scholar]
13. Herold J., Andino R. 2000b; Poliovirus requires a precise 5′ end for efficient positive-strand RNA synthesis. Journal of Virology 74:6394–6400
    [Google Scholar]
14. Ito T., Lai M. M. C. 1999; An internal polypyrimidine-tract-binding protein-binding site in the hepatitis C virus RNA attenuates translation, which is relieved by the 3′-untranslated sequence. Virology 254:288–296
    [Google Scholar]
15. Ito T., Tahara S. M., Lai M. M. C. 1998; The 3′-untranslated region of hepatitis C virus RNA enhances translation from an internal ribosomal entry site. Journal of Virology 72:8789–8796
    [Google Scholar]
16. Kitching R. P. 1999; Foot-and-mouth disease: current world situation. Vaccine 26:1772–1774
    [Google Scholar]
17. Kühn R., Luz N., Beck E. 1990; Functional analysis of the internal translation initiation site of foot-and-mouth disease virus. Journal of Virology 64:4625–4631
    [Google Scholar]
18. Kunkel T. 1985; Rapid and efficient site specific mutagenesis without phenotypic selection. Proceedings of the National Academy of Sciences, USA 82:488–492
    [Google Scholar]
19. Lobert P. E., Escriou N., Ruelle J., Michiels T. 1999; A coding RNA sequence acts as a replication signal in cardioviruses. Proceedings of the National Academy of Sciences, USA 96:11560–11565
    [Google Scholar]
20. López de Quinto S., Martínez-Salas E. 1997; Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation. Journal of Virology 71:4174–4175
    [Google Scholar]
21. Lu H. H., Wimmer E. 1996; Poliovirus chimeras replicating under the translational control of genetic elements of hepatitis C virus reveal unusual properties of the internal ribosomal entry site of hepatitis C virus. Proceedings of the National Academy of Sciences, USA 93:1412–1417
    [Google Scholar]
22. McInerney G. M., King A. M., Ross-Smith N., Belsham G. J. 2000; Replication-competent foot-and-mouth disease virus RNAs lacking capsid coding sequences. Journal of General Virology 81:1699–1702
    [Google Scholar]
23. McKnight K. L., Lemon S. M. 1998; The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication. RNA 4:1569–1584
    [Google Scholar]
24. Mellits K. H., Meredith J. M., Rohll J. B., Evans D. J., Almond J. W. 1998; Binding of a cellular factor to the 3′ untranslated region of the RNA genomes of entero- and rhinoviruses plays a role in virus replication. Journal of General Virology 79:1715–1723
    [Google Scholar]
25. Paul A. V., Rieder E., Kim D. W., Wimmer E. 2000; Identification of an RNA hairpin in poliovirus RNA that serves as a specific template for the uridylylation of VPg in vitro. Europic 2000 (Zagare Bay, Gargano, Italy, 25–31 May 2000). Abstract E04
    [Google Scholar]
26. Pierangeli A., Bucci M., Pagnotti P., Degener A. M., Perez Bercoff R. 1995; Mutational analysis of the 3’-terminal extra-cistronic region of poliovirus RNA: secondary structure is not the only requirement for minus-strand RNA replication. FEBS Letters 374:327–332
    [Google Scholar]
27. Pilipenko E. V., Maslova S. V., Sinyakov A. N., Agol V. I. 1992; Towards identification of cis -acting elements involved in the replication of enterovirus and rhinovirus RNAs: a proposal for the existence of tRNA-like terminal structures. Nucleic Acids Research 20:1739–1745
    [Google Scholar]
28. Richards O. C., Ehrenfeld E. 1990; Poliovirus RNA replication . Current Topics in. Microbiology and Immunology 161:89–119
    [Google Scholar]
29. Rohll J. B., Percy N., Ley R., Evans D. J., Almond J. W., Barclay W. S. 1994; The 5′-untranslated regions of picornavirus RNAs contain independent functional domains essential for RNA replication and translation. Journal of Virology 68:4384–4391
    [Google Scholar]
30. Rohll J. B., Moon D. H., Evans D. J., Almond J. W. 1995; The 3′ untranslated region of picornavirus RNA: features required for efficient genome replication. Journal of Virology 69:7835–7844
    [Google Scholar]
31. Rose J. K., Buonocore L., Whitt M. A. 1991; A new cationic liposome reagent mediating nearly quantitative transfection of animal cells. Biotechniques 10:520–525
    [Google Scholar]
32. Rueckert R. R. 1990; Picornaviridae and their replication. In Fields Virology pp 507–548 Edited by Fields B. N., Knipe D. M. New York: Raven Press;
    [Google Scholar]
33. Ryan M. D., Belsham G. J., King A. M. 1989; Specificity of enzyme-substrate interactions in foot-and-mouth disease virus polyprotein processing. Virology 173:35–45
    [Google Scholar]
34. Sangar D. V., Rowlands D. J., Harris T. J. R., Brown F. 1977; A protein covalently linked to foot-and-mouth disease virus RNA. Nature 268:648–650
    [Google Scholar]
35. Seechurn P., Knowles N. J., McCauley J. W. 1990; The nucleotide sequence of a pathogenic swine vesicular disease virus. Virus Research 16:255–274
    [Google Scholar]
36. Sutmoller P. 1992; Vesicular diseases, foreign animal diseases. In Committee Report on Foreign Animal Diseases of the United States Animal Health Association pp 368–382 Richmond, VA, USA:
    [Google Scholar]
37. Todd S., Semler B. L. 1996; Structure-infectivity analysis of the human rhinovirus genomic RNA 3′ noncoding region. Nucleic Acids Research 24:2133–2142
    [Google Scholar]
38. Todd S., Nguyen J. H., Semler B. L. 1995; RNA-protein interactions directed by the 3′ end of human rhinovirus genomic RNA. Journal of Virology 69:3605–3614
    [Google Scholar]
39. Todd S., Towner J. S., Brown D. M., Semler B. L. 1997; Replication-competent picornavirus with complete genomic RNA 3′ noncoding region deletions. Journal of Virology 71:8868–8874
    [Google Scholar]
40. Waggoner S., Sarnow P. 1998; Viral ribonucleoprotein complex formation and nucleolar-cytoplasmic relocalization of nucleolin in poliovirus-infected cells. Journal of Virology 72:6699–6709
    [Google Scholar]
41. Zibert A., Maas G., Strebe l. K., Falk M. M., Beck E. 1990; Infectious foot-and-mouth disease virus derived from a cloned full-length cDNA. Journal of Virology 64:2467–2473
    [Google Scholar]