DNA encoding the attachment (G) or fusion (F) protein of respiratory syncytial virus induces protection in the absence of pulmonary inflammation

References

1. Alwan W. H., Openshaw P. J. M. 1993; Distinct patterns of T- and B-cell immunity to respiratory syncytial virus induced by individual viral proteins. Vaccine 11:431–437
   [Google Scholar]
2. Alwan W. H., Record F. M., Openshaw P. J. 1993; Phenotypic and functional characterization of T cell lines specific for individual respiratory syncytial virus proteins. Journal of Immunology 150:5211–5218
   [Google Scholar]
3. Bembridge G. P., Garcia-Beato R., Lopez J. A., Melero J. A., Taylor G. 1998 a; Subcellular site of expression and route of vaccination influence pulmonary eosinophilia following respiratory syncytial virus challenge in BALB/c mice sensitized to the attachment G protein. Journal of Immunology 161:2473–2480
   [Google Scholar]
4. Bembridge G. P., Lopez J. A., Cook R., Melero J. A., Taylor G. 1998 b; Recombinant vaccinia virus coexpressing the F protein of respiratory syncytial virus (RSV) and interleukin-4 (IL-4) does not inhibit the development of RSV-specific memory cytotoxic T lymphocytes, whereas priming is diminished in the presence of high levels of IL-2 or gamma interferon. Journal of Virology 72:4080–4087
   [Google Scholar]
5. Bembridge G. P., Lopez J. A., Bustos R., Melero J. A., Cook R., Mason H., Taylor G. 1999; Priming with a secreted form of the fusion protein of respiratory syncytial virus (RSV) promotes interleukin-4 (IL-4) and IL-5 production but not pulmonary eosinophilia following RSV challenge. Journal of Virology 73:10086–10094
   [Google Scholar]
6. Connors M., Kulkarni A. B., Firestone C.-Y., Holmes K. L., Morse H. C.III., Sotnikov A. V., Murphy B. R. 1992; Pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of CD4+ T cells. Journal of Virology 66:7444–7451
   [Google Scholar]
7. Connors M., Giese N. A., Kulkarni A. B., Firestone C. Y., Morse H. C.III., Murphy B. R. 1994; Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10. Journal of Virology 68:5321–5325
   [Google Scholar]
8. Donnelly J. J., Ulmer J. B., Shiver J. W., Liu M. A. 1997; DNA vaccines. Annual Review of Immunology 15:617–648
   [Google Scholar]
9. Feltquate D. M., Heaney S., Webster R. G., Robinson H. L. 1997; Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization. Journal of Immunology 158:2278–2284
   [Google Scholar]
10. Graham B. S., Henderson G. S., Tang Y. W., Lu X., Neuzil K. M., Colley D. G. 1993; Priming immunization determines T helper cytokine mRNA expression patterns in lungs of mice challenged with respiratory syncytial virus. Journal of Immunology 151:2032–2040
    [Google Scholar]
11. Hussell T., Khan U., Openshaw P. 1997; IL-12 treatment attenuates T helper cell type 2 and B cell responses but does not improve vaccine-enhanced lung illness. Journal of Immunology 159:328–334
    [Google Scholar]
12. Li X., Sambhara S., Li C. X., Ewasyshyn M., Parrington M., Caterini J., James O., Cates G., Du R.-P., Klein M. 1998; Protection against respiratory syncytial virus infection by DNA immunization. Journal of Experimental Medicine 188:681–688
    [Google Scholar]
13. Lim Y. S., Kang B. Y., Kim E. J., Kim S. H., Hwang S. Y., Kim T. S. 1998; Potentiation of antigen-specific, Th1 immune responses by multiple DNA vaccination with an ovalbumin/interferon-γ hybrid construct. Immunology 94:135–141
    [Google Scholar]
14. Openshaw P. J., Clarke S. L., Record F. M. 1992; Pulmonary eosinophilic response to respiratory syncytial virus infection in mice sensitized to the major surface glycoprotein G. International Immunology 4:493–500
    [Google Scholar]
15. Pertmer T. M., Roberts T. R., Haynes J. R. 1996; Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery. Journal of Virology 70:6119–6125
    [Google Scholar]
16. Schrijver R. S., Langedijk J. P. M., Keil G. M., Middel W. G. J., Maris-Veldhuis M., van Oirschot J. T., Rijsewijk F. A. M. 1997; Immunization of cattle with a BHV1 vector vaccine or a DNA vaccine both coding for the G protein of BRSV. Vaccine 15:1908–1916
    [Google Scholar]
17. Seder R. A., Paul W. E. 1994; Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annual Review of Immunology 12:635–673
    [Google Scholar]
18. Stott E. J., Taylor G., Ball L. A., Anderson K., Young K. K.-Y., King A. M. Q., Wertz G. W. 1987; Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus. Journal of Virology 61:3855–3861
    [Google Scholar]
19. Swain S. L., Weinberg A. D., English M., Huston G. 1990; IL-4 directs the development of Th2-like helper effectors. Journal of Immunology 145:3796–3806
    [Google Scholar]
20. Tang Y. W., Graham B. S. 1995; Interleukin-12 treatment during immunization elicits a T helper cell type 1-like immune response in mice challenged with respiratory syncytial virus and improves vaccine immunogenicity. Journal of Infectious Diseases 172:734–738
    [Google Scholar]
21. Taylor G., Stott E. J., Hughes M., Collins A. P. 1984; Respiratory syncytial virus infection in mice. Infection and Immunity 43:649–655
    [Google Scholar]
22. Tripp R. A., Moore D., Jones L., Sullender W., Winter J., Anderson L. J. 1999; Respiratory syncytial virus G and/or SH protein alters Th1 cytokines, natural killer cells, and neutrophils responding to pulmonary infection in BALB/c mice. Journal of Virology 73:7099–7107
    [Google Scholar]
23. Xiang Z., Ertl H. C. 1995; Manipulation of the immune response to a plasmid-encoded viral antigen by coinoculation with plasmids expressing cytokines. Immunity 2:129–135
    [Google Scholar]