1887

Abstract

Molecular epidemiology studies have made significant contributions to the control of measles virus infection through the identification of source and transmission pathways of the virus. These studies allow observation of changes in measles virus genotypes over time in a particular geographical location, clarification of epidemiological links during measles outbreaks, separation of indigenous strains from newly imported strains and distinction between vaccine- and wild-type virus-associated illness. A total of 35 wild-type measles viruses identified in Victoria, Australia, between 1973 and 1998 were characterized by nucleic acid sequence analysis of the nucleoprotein gene and, in some cases, the haemagglutinin gene. Relatedness between the viruses was studied and genotypes were assigned using a classification scheme recently proposed by the World Health Organization. Five recognized genotypes (C2, D1, D4, D5 and H) and one previously undescribed genotype, which we propose to be D7, were identified. Successive replacement of measles virus genetic lineages occurred in Victoria, with no evidence of temporal overlap, during this 25 year period. This pattern of circulation is likely to represent serial importation of wild-type measles virus strains from overseas foci of measles virus infections.

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2000-10-01
2024-04-25
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References

  1. Bellini W. J., Rota P. A. 1998; Genetic diversity of wild-type measles viruses: implications for global measles elimination programs. Emerging Infectious Diseases 4:29–35
    [Google Scholar]
  2. Chomczynski P., Sacchi N. 1987; Single-step method of RNA isolation by acid guanidinium thiocyanate–phenol–chloroform extraction. Analytical Biochemistry 162:156–159
    [Google Scholar]
  3. Corpet F. 1988; Multiple sequence alignment with hierarchical clustering. Nucleic Acids Research 16:10881–10890
    [Google Scholar]
  4. de Swart R. L., Wertheim van Dillen P. M. E., van Binnendijk R. S., Muller C. P., Frenkel J., Osterhaus A. D. M. E. 2000; Measles in a Dutch hospital introduced by an immuno-compromised infant from Indonesia infected with a new virus genotype. Lancet 355:201–202
    [Google Scholar]
  5. Felsenstein J. 1993 PHYLIP: Phylogeny inference package, version 3.5c University of Washington; Seattle, WA, USA:
    [Google Scholar]
  6. Hanses F., Truong A. T., Ammerlann W., Ikusika O., Adu F., Oyefolu A. O., Omilabu S. A., Muller C. P. 1999; Molecular epidemiology of Nigerian and Ghanaian measles virus isolates reveals a genotype circulating widely in western and central Africa. Journal of General Virology 80:871–877
    [Google Scholar]
  7. Jin L., Brown D. W. G., Ramsay M. E. B., Rota P. A., Bellini W. J. 1997; The diversity of measles virus in the United Kingdom, 1992–1995. Journal of General Virology 78:1287–1294
    [Google Scholar]
  8. Kreis S., Vardas E., Whistler T. 1997; Sequence analysis of the nucleocapsid gene of measles virus isolates from South Africa identifies a new genotype. Journal of General Virology 78:1581–1587
    [Google Scholar]
  9. Lambert S. B., Kelly H. A., Andrews R. M., Catton M. C., Lynch P. A., Leydon J. L., Gercovich D. K., Hogg G. G., Morgan M. L., Lester R. A. 2000; Enhanced measles surveillance during an interepidemic period in Victoria. Medical Journal of Australia 172:114–118
    [Google Scholar]
  10. McIntyre P. B., Gidding H. F., Gilbert G. L. 2000; Measles in an era of measles control. Medical Journal of Australia 172:103–104
    [Google Scholar]
  11. Nicholas K. B., Nicholas H. B. Jr 1997; Genedoc: a tool for editing and annotating multiple sequence alignments. Distributed by the author
  12. Page R. D. M. 1996; TreeView: an application to display phylogenetic trees on personal computers. Computer Applications in the Biosciences 12:357–358
    [Google Scholar]
  13. Rima B. K., Earle J. A. P., Yeo R. P., Herlihy L., Baczko K., ter Meulen V., Carabaña J., Caballero M., Celma M. L., Fernandez-Muñoz R. 1995; Temporal and geographical distribution of measles virus genotypes. Journal of General Virology 76:1173–1180
    [Google Scholar]
  14. Rima B. K., Earle J. A. P., Baczko K., ter Meulen V., Liebert U. G., Carstens C., Carabaña J., Caballero M., Celma M. L., Fernandez-Muñoz R. 1997; Sequence divergence of measles virus haemagglutinin during natural evolution and adaptaton to cell culture. Journal of General Virology 78:97–106
    [Google Scholar]
  15. Rota P. A., Bloom A. E., Vanchieri J. A., Bellini W. J. 1994; Evolution of the nucleoprotein and matrix genes of wild-type strains of measles virus isolated from recent epidemics. Virology 198:724–730
    [Google Scholar]
  16. Rota J. S., Heath J. L., Rota P. A., King G. E., Celma M. L., Carabaña J., Fernandez-Muñoz R., Brown D., Jin L., Bellini W. J. 1996; Molecular epidemiology of measles virus: identification of pathways of transmission and implications for measles elimination. Journal of Infectious Diseases 173:32–37
    [Google Scholar]
  17. Rota J. S., Rota P. A., Redd S. B., Redd S. C., Pattamadilok S., Bellini W. J. 1998; Genetic analysis of measles viruses isolated in the United States, 1995–1996. Journal of Infectious Diseases 177:204–208
    [Google Scholar]
  18. Santibanez S., Heider A., Gerike E., Agafonov A., Schreier E. 1999; Genotyping of measles virus isolates from Central Europe and Russia. Journal of Medical Virology 58:313–320
    [Google Scholar]
  19. Tobin S., Kelly H. 1999; Measles encephalitis in Victoria, 1962–1996: down but not out. Australian and New Zealand Journal of Public Health 23:443
    [Google Scholar]
  20. WHO 1998; Expanded programme on immunization – standardization of the nomenclature for describing the genetic characteristics of wild-type measles viruses. Weekly Epidemiological Record 73:265–269
    [Google Scholar]
  21. WHO 1999; Measles. Progress towards global control and regional elimination 1998–1999. Weekly Epidemiological Record 74:429–440
    [Google Scholar]
  22. Xu W., Tamin A., Rota J. S., Zhang L., Bellini W. J., Rota P. A. 1998; New genetic group of measles virus isolated in the People’s Republic of China. Virus Research 54:147–156
    [Google Scholar]
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