1887

Abstract

The development of the antibody response to peptides of the transmembrane glycoprotein of bovine immunodeficiency virus (BIV) was followed over a period of 50 weeks in six cattle experimentally infected with the BIV(FL112) isolate. Antibody was detected by an enzyme immunoassay using either a linear or a cyclized peptide with structural features common to an immunodominant region of other lentiviruses. The assay was specific for BIV, detecting antibody in bovine sera to BIV(FL112) or BIV(R29) but not to six other common viruses of cattle. Antibody was present in the sera of all cattle inoculated with BIV(FL112) within 4 weeks of infection, peaked between 10 and 30 weeks and persisted in most cattle during the 50 weeks of observation. These features indicate that this assay may be useful in identifying cattle infected with other strains of BIV in the field.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-80-1-237
1999-01-01
2022-09-25
Loading full text...

Full text loading...

/deliver/fulltext/jgv/80/1/0800237a.html?itemId=/content/journal/jgv/10.1099/0022-1317-80-1-237&mimeType=html&fmt=ahah

References

  1. Amborski G. F., Lo J. L., Seger C. L. 1989; Serological detection of multiple retroviral infections in cattle: bovine leukemia virus, bovine syncytial virus and bovine visna virus. Veterinary Microbiology 20:247–253
    [Google Scholar]
  2. Avrameas A., Guillet J. G., Chouchane L., Mouraillon A., Sonigo P., Strosberg A. D. 1992; Localisation of three epitopes of the env protein of feline immunodeficiency virus. Molecular Immunology 29:565–572
    [Google Scholar]
  3. Bertoni G., Zhano M. L., Zanoni R., Vogt H. R., Peterhans E., Ruff G., Cheevers W. P., Sonigo P., Pancino G. 1994; Antibody reactivity to the immunodominant epitopes of the caprine arthritis-encephalitis virus gp38 transmembrane protein associates with the development of arthritis. Journal of Virology 68:7139–7147
    [Google Scholar]
  4. Chen P., Liu Z. Q., Wood C. 1994; Use of TrpE fusion protein to identify antigenic domains within the BIV envelope protein. Journal of Virological Methods 47:331–343
    [Google Scholar]
  5. Chong Y. H., Ball J. M., Issel C. J., Montelaro R. C., Rushlow K. E. 1991; Analysis of equine humoral immune responses to the transmembrane envelope glycoprotein (gp45) of equine infectious anemia virus. Journal of Virology 65:1013–1018
    [Google Scholar]
  6. Cockerell G. L., Jensen W. A., Rovnak J., Ennis W. H., Gonda M. A. 1992; Seroprevalence of bovine immunodeficiency-like virus and bovine leukemia virus in a dairy cattle herd. Veterinary Microbiology 31:109–116
    [Google Scholar]
  7. Fontenot J. D., Hoover E. A., Elder J. H., Montelaro R. C. 1992; Evaluation of feline immunodeficiency virus and feline leukemia virus transmembrane peptides for serological diagnosis. Journal of Clinical Microbiology 30:1885–1890
    [Google Scholar]
  8. Gallacher W. R., Ball J. M., Garry R. F., Griffin M. C., Montelaro R. C. 1989; A general model for the transmembrane proteins of HIV and other retroviruses. AIDS Research and Human Retroviruses 5:431–440
    [Google Scholar]
  9. Gnann J. W., Nelson J. A., Oldstone M. A. B. 1987; Fine mapping of an immunodominant domain in the transmembrane glycoprotein of human immunodeficiency virus. Journal of Virology 61:2639–2641
    [Google Scholar]
  10. Gonda M. A., Luther D. G., Fong S. E., Tobin G. J. 1994; Bovine immunodeficiency virus: molecular biology and virus−host interactions. Virus Research 32:155–181
    [Google Scholar]
  11. Horner G. W. 1991; Serological evidence of bovine immunodeficiency-like virus and bovine syncytial virus in New Zealand. Surveillance 18:9
    [Google Scholar]
  12. Horzinek M., Keldermans L., Stuurman T., Black J., Herrewegh A., Sillekens P., Koolen M. 1991; Bovine immunodeficiency virus: immunochemical characterization and serological survey. Journal of General Virology 72:2923–2928
    [Google Scholar]
  13. Isaacson J. A., Roth J. A., Wood C., Carpenter S. 1995; Loss of Gag-specific antibody reactivity in cattle experimentally infected with bovine immunodeficiency-like virus. Viral Immunology 8:27–36
    [Google Scholar]
  14. McNab W. B., Jacobs R. M., Smith H. E. 1994; A serological survey for bovine immunodeficiency-like virus in Ontario cattle and associations between test results, production records and management practices. Canadian Journal of Veterinary Research 58:151–181
    [Google Scholar]
  15. Munro R., Lysons R., Venables C., Horigan M., Jeffrey M., Dawson M. 1998; Lymphadenopathy and non-suppurative meningo-encepha-litis in calves experimentally infected with bovine immunodeficiency-like virus. Journal of Comparative Pathology 119:121–134
    [Google Scholar]
  16. Pancino G., Camoin L., Sonigo P. 1995; Structural analysis of the principal immunodominant domain of the feline immunodeficiency virus transmembrane glycoprotein. Journal of Virology 69:2110–2118
    [Google Scholar]
  17. Polack B., Schwartz I., Berthelemy M., Belloc C., Manet G., Vuillaume A., Baron T., Gonda M. A., Levy D. 1996; Serologic evidence for bovine immunodeficiency virus infection in France. Veterinary Microbiology 48:165–173
    [Google Scholar]
  18. St Cyr Coats K., Pruett S. B., Nash J. W., Cooper C. R. 1994; Bovine immunodeficiency virus: incidence of infection in Mississippi dairy cattle. Veterinary Microbiology 42:181–189
    [Google Scholar]
  19. Sibille P., Avrameas A., Moraillon A., Richardson J., Sonigo P., Pancino G., Strosberg A. D. 1995; Comparison of serological tests for the diagnosis of feline immunodeficiency virus infection of cats. Veterinary Microbiology 45:259–267
    [Google Scholar]
  20. Suarez D. L., Whetstone C. A. 1995; Identification of hypervariable and conserved regions in the surface envelope gene in the bovine lentivirus. Virology 212:728–733
    [Google Scholar]
  21. Suarez D. L., VanDerMaaten M. J., Wood C., Whetstone C. A. 1993; Isolation and characterization of new wild-type isolates of bovine lentivirus. Journal of Virology 67:5051–5055
    [Google Scholar]
  22. Van der Maaten M. J., Boothe A. D., Seger C. L. 1972; Isolation of a virus from cattle with persistent lymphocytosis. Journal of the National Cancer Institute 49:1649–1657
    [Google Scholar]
  23. Venables C., Lysons R., Horigan M., Stagg D., Dawson M. 1997; Bovine immunodeficiency-like virus: inactivation in milk by pasteurisation. Veterinary Record 140:275–277
    [Google Scholar]
  24. Whetstone C. A., VanDerMaaten M. J., Black J. W. 1990; Humoral immune response to the bovine immunodeficiency-like virus in experimentally and naturally infected cattle. Journal of Virology 64:3557–3561
    [Google Scholar]
  25. Whetstone C. A., VanDerMaaten M. J., Miller J. M. 1991; Awestern blot assay for the detection of antibodies to bovine immunodeficiency-like virus in experimentally inoculated cattle, sheep, and goats. Archives of Virology 116:119–131
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-80-1-237
Loading
/content/journal/jgv/10.1099/0022-1317-80-1-237
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error