The bovine papillomavirus type 4 long control region contains an epithelial specific enhancer.

References

1. Apt D., Chong T., Liu Y., Bernard H. U. 1993; Nuclear factor I and epithelial cell-specific transcription of human papillomavirus type 16. Journal of Virology 67:4455–4463
   [Google Scholar]
2. Apt D., Liu Y., Bernard H. U. 1994; Cloning and functional analysis of spliced isoforms of human nuclear factor I-X: interference with transcriptional activation by NF1/CTF in a cell-type specific manner. Nucleic Acids Research 22:3825–3833
   [Google Scholar]
3. Apt D., Watts R. M., Suske G., Bernard H. U. 1996; High Sp1/Sp3 ratios in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter. Virology 224:281–291
   [Google Scholar]
4. Bauknecht T., Shi Y. 1998; Overexpression of C/EBPβ represses human papillomavirus type 18 upstream regulatory region activity in HeLa cells by interfering with the binding of TATA-binding protein. Journal of Virology 72:2113–2124
   [Google Scholar]
5. Bauknecht T., See R. H., Shi Y. 1996; A novel C/EBPβ–YY1 complex controls the cell-type-specific activity of the human papillomavirus type 18 upstream regulatory region. Journal of Virology 70:7695–7705
   [Google Scholar]
6. Campo M. S., O′Neil B. W., Barron R. J., Jarrett W. F. H. 1994; Experimental reproduction of the papilloma-carcinoma complex of the alimentary canal in cattle. Carcinogenesis 15:1597–1601
   [Google Scholar]
7. Chong T., Apt D., Gloss B., Isa M., Bernard H. U. 1991; The enhancer of human papillomavirus type 16: binding sites for the ubiquitous transcription factors oct-1, NFA, TEF-2, NF1, and AP-1 participate in epithelial cell-specific transcription. Journal of Virology 65:5933–5943
   [Google Scholar]
8. Cuthill S., Sibbet G. J., Campo M. S. 1993; Characterization of a nuclear factor, papilloma enhancer binding factor-1, that binds the long control region of human papillomavirus type 16 and contributes to enhancer activity. Molecular Carcinogenesis 8:96–104
   [Google Scholar]
9. Desaintes C., Demeret C. 1996; Control of papillomavirus DNA replication and transcription. Seminars in Cancer Biology 7:339–347
   [Google Scholar]
10. Dong X. P., Stubenrauch F., Beyer-Finkler E., Pfister H. 1994; Prevalence of deletions of YY1-binding sites in episomal HPV 16 DNA from cervical cancers. International Journal of Cancer 58:803–808
    [Google Scholar]
11. Gloss B., Bernard H. U., Seedorf K., Klock G. 1987; The upstream regulatory region of the human papilloma virus-16 contains an E2 protein-independent enhancer which is specific for cervical carcinoma cells and regulated by glucocorticoid hormones. EMBO Journal 6:3735–3743
    [Google Scholar]
12. Gloss B., Chong T., Bernard H. U. 1989; Numerous nuclear proteins bind the long control region of human papillomavirus type 16: a subset of 6 of 23 DNase I-protected segments coincides with the location of the cell-type-specific enhancer. Journal of Virology 63:1142–1152
    [Google Scholar]
13. Hoppe-Seyler F., Butz K., zur Hausen H. 1991; Repression of the human papillomavirus type 18 enhancer by the cellular transcription factor Oct-1. Journal of Virology 65:5613–5618
    [Google Scholar]
14. Jackson M. E., Campo M. S. 1991; Positive and negative E2-independent regulatory elements in the long control region of bovine papillomavirus type 4. Journal of General Virology 72:877–883
    [Google Scholar]
15. Jackson M. E., Campo M. S. 1995; Both viral E2 protein and the cellular factor PEBP2 regulate transcription via E2 consensus sites within the bovine papillomavirus type 4 long control region. Journal of Virology 69:6038–6046
    [Google Scholar]
16. McCaffery R. E., Jackson M. E. 1994; An element binding a C/EBP-related transcription factor contributes to negative regulation of the bovine papillomavirus type 4 long control region. Journal of General Virology 75:3047–3056
    [Google Scholar]
17. Morgan I. M., Grindlay G. J., Campo M. S. 1998; Epithelial specific transcriptional regulation of the bovine papillomavirus 4 promoter by E2. Journal of General Virology 79:501–508
    [Google Scholar]
18. Morris P. J., Dent C. L., Ring C. J., Latchman D. S. 1993; The octamer binding site in the HPV-16 regulatory region produces opposite effects on gene expression in cervical and non-cervical cells. Nucleic Acids Research 21:1019–1023
    [Google Scholar]
19. Nakshatri H., Pater M. M., Pater A. 1990; Ubiquitous and cell-type-specific protein interactions with human papillomavirus type 16 and type 18 enhancers. Virology 178:92–103
    [Google Scholar]
20. O′Connor M., Bernard H. U. 1995; Oct-1 activates the epithelial-specific enhancer of human papillomavirus type 16 via a synergistic interaction with NF1 at a conserved composite regulatory element. Virology 207:77–88
    [Google Scholar]
21. O′Connor M. J., Tan S. H., Tan C. H., Bernard H. U. 1996; YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity. Journal of Virology 70:6529–6539
    [Google Scholar]
22. Offord E. A., Beard P. 1990; A member of the activator protein 1 family found in keratinocytes but not in fibroblasts required for transcription from a human papillomavirus type 18 promoter. Journal of Virology 64:4792–4798
    [Google Scholar]
23. Sibbet G. J., Cuthill S., Campo M. S. 1995; The enhancer in the long control region of human papillomavirus type 16 is up-regulated by PEF-1 and down-regulated by Oct-1. Journal of Virology 69:4006–4011
    [Google Scholar]
24. Thierry F., Spyrou G., Yaniv M., Howley P. 1992; Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytes. Journal of Virology 66:3740–3748
    [Google Scholar]
25. Wang H., Liu K., Yuan F., Berdichevsky L., Taichman L. B., Auborn K. 1996; C/EBPβ is a negative regulator of human papillomavirus type 11 in keratinocytes. Journal of Virology 70:4839–4844
    [Google Scholar]
26. zur Hausen H. 1991; Human papillomaviruses in the pathogenesis of anogenital cancer. Virology 184:9–13
    [Google Scholar]