Two types of experiment have been made during the early part of the latent period on a culture of cells singly infected with phage T4.

First, samples taken from the infected cells at different times were irradiated with ultraviolet light in order to obtain a set of Luria-Latarjet curves. Secondly, and with the same culture of infected cells, the kinetics of phage DNA synthesis was followed using a density gradient technique.

A comparison of these results suggests that the radiation stability shown by the Luria-Latarjet curves is first detectable at about the time that phage DNA synthesis commences. The radiation stability, however, increases at a rate which is much faster than the rate of replication of the parental phage DNA.


Article metrics loading...

Loading full text...

Full text loading...


Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error