RT Journal Article SR Electronic(1) A1 Powell, R. M. A1 Schmitt, V. A1 Ward, T. A1 Goodfellow, I. A1 Evans, D. J. A1 Almond, J. W.YR 1998 T1 Characterization of echoviruses that bind decay accelerating factor (CD55): evidence that some haemagglutinating strains use more than one cellular receptor JF Journal of General Virology, VO 79 IS 7 SP 1707 OP 1713 DO https://doi.org/10.1099/0022-1317-79-7-1707 PB Microbiology Society, SN 1465-2099, AB Several echoviruses (EVs) have previously been shown to use decay accelerating factor (DAF) as a cellular receptor. Since DAF is expressed on erythrocytes, EVs that use this receptor cause haemag- glutination. Here we show that all EVs that haemag- glutinate do so via attachment to DAF and that this interaction can be inhibited by a monoclonal anti-body (MAb) specific for DAF domain SCR3. Although the viruses haemagglutinate via DAF some can bind to rhabdomyosarcoma cells from which DAF has been removed and infect in the presence of a MAb against DAF. This suggests that some EVs have the capacity to interact with more than one cellular receptor., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-79-7-1707