RT Journal Article SR Electronic(1) A1 Whitehouse, Adrian A1 Stevenson, Alex J. A1 Cooper, Matthew A1 Meredith, David M.YR 1997 T1 Identification of a cis-acting element within the herpesvirus saimiri ORF 6 promoter that is responsive to the HVS.R transactivator JF Journal of General Virology, VO 78 IS 6 SP 1411 OP 1415 DO https://doi.org/10.1099/0022-1317-78-6-1411 PB Microbiology Society, SN 1465-2099, AB We have previously demonstrated that two distinct transcripts are produced from ORF 50, the major transcriptional activating gene of herpesvirus saimiri. The products of these transcripts trans- activate the delayed-early ORF 6 promoter, though to different degrees. Deletion analysis demonstrated that the ORF 50 responsive elements are contained in a 132 bp fragment situated 127–259 bp from the transcription initiation site within the ORF 6 promoter. This fragment conferred ORF 50-responsiveness on an enhancerless simian virus 40. Gel retardation analysis further mapped the responsive elements to a 38 bp fragment., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-78-6-1411