1887

Abstract

The complete DNA sequence of a field strain of canine adenovirus type 1 was determined by sequencing random fragments of viral DNA cloned into pBluescript. The virus has a genome of 30536 bp flanked by two identical 161 bp inverted terminal repeats. Thirty ORFs have been identified, based on genomic location or sequence identity with published adenoviruses. These are arranged into similar discrete regions found in the human adenoviruses. ORFs in the late region show greatest identity with published human adenovirus sequences, whereas the E3 and E4 ORFs show little or none.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-78-4-873
1997-04-01
2024-12-05
Loading full text...

Full text loading...

/deliver/fulltext/jgv/78/4/9129661.html?itemId=/content/journal/jgv/10.1099/0022-1317-78-4-873&mimeType=html&fmt=ahah

References

  1. Akusjärvi G., Pettersson U., Roberts R. J. 1986; . Adenovirus DNA chapter 2 pp. 53–95 Doerfler W. Edited by Boston: Martinus Nijhoff;
    [Google Scholar]
  2. Bairoch A. 1995 Prosite: a dictionary of protein sites and patterns, release 12.2, February 1995 Distributed by the European Bioinformatics Institute, Cambridge, UK:
    [Google Scholar]
  3. Cai F., Weber J. M. 1992; Nucleotide and deduced amino acid sequence of the canine adenovirus type 1 proteinase. Virus and Genes 6:307–312
    [Google Scholar]
  4. Cai F., Weber J. M. 1993; Primary structure of the canine adenovirus pVII protein: functional implications. Virology 193:986–988
    [Google Scholar]
  5. Carthew R. W., Chodosh L. A., Sharp P. A. 1985; An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell 43:439–448
    [Google Scholar]
  6. Chiocca S., Kurzbauer R., Schaffner G., Baker A., Mautner V., Cotten M. 1996; The complete DNA sequence and genomic organization of the avian adenovirus CELO. Journal of Virology 70:2939–2949
    [Google Scholar]
  7. Chodosh L. A., Carthew R. W., Sharp P. A. 1986; A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Molecular and Cellular Biology 6:4723–4733
    [Google Scholar]
  8. Chroboczek J., Bieber F., Jacrot B. 1992; The sequence of the genome of adenovirus type 5 and its comparison with the genome of adenovirus type 2. Virology 186:280–285
    [Google Scholar]
  9. Davison A. J., Telford E. A. R. 1994; Large scale DNA sequencing by manual methods. Methods in Gene Technology 2:151–175
    [Google Scholar]
  10. Davison A. J., Telford E. A. R., Watson M. S., McBride K., Mautner V. 1993; The DNA sequence of adenovirus type 40. Journal of Molecular Biology 234:1308–1316
    [Google Scholar]
  11. Dragulev B. P., Sira S., Abouhaidar M. G., Campbell J. B. 1991; Sequence analysis of putative E3 and fibre genomic regions of two strains of canine adenovirus type 1. Virology 183:298–305
    [Google Scholar]
  12. Genetics Computer Group 1995 Program manualfor theGCG package, version 8.1, August 1995 Genetics Computer Group, 575 Science Drive, Madison, WI 53711, USA:
    [Google Scholar]
  13. Ginsberg H. S. 1988; Adenoviruses. In Virology, 2nd edn. chapter 2 pp. 147–160 Biello L. A., Winters R., Henderson L. Edited by Philadelphia: Lippincott Press;
    [Google Scholar]
  14. Gräble M., Hearing P. 1990; Adenovirus type 5 packaging domain is composed of a repeated element that is functionally redundant. Journal of Virology 64:2047–2056
    [Google Scholar]
  15. Hay R. T. 1985; The origin of adenovirus DNA replication: minimal DNA sequence requirement in vivo. EMBO Journal 4:421–426
    [Google Scholar]
  16. Koptopoulos G., Cornwell H. J. C. 1981; Canine adenoviruses: a review. Veterinary Bulletin 51:135–142
    [Google Scholar]
  17. Linne T. 1992; Differences in the E3 regions of canine adenovirus type 1 and type 2. Virus Research 23:119–133
    [Google Scholar]
  18. Nicolson L., Rafferty E. L., Brawley A., Onions D. E. 1994; An improved cosmid vector for the cloning of equine herpesvirus DNA. Gene 150:405–406
    [Google Scholar]
  19. Precious B., Russell W. C. 1985; Growth, purification and titration of adenoviruses. In Virology, a Practical Approach pp. 193–205 Mahy B. W. J. Edited by Oxford: IRL Press;
    [Google Scholar]
  20. Roberts R. J., Akusjärvi G., Aleström P., Gelinas R. E., Gingeras T. R., Sciaky D., Pettersson U. 1986 Adenovirus DNA chapter 1 pp. 1–51 Doerfler W. Edited by Boston: Martinus Nijhoff;
    [Google Scholar]
  21. Shibata R., Shinagawa M., Iida Y., Tsukiyama T. 1989; Nucleotide sequence of E1 region of canine adenovirus type 2. Virology 172:460–467
    [Google Scholar]
  22. Shinagawa M., Ishiyama T., Padmanabhan R., Fujinaga K., Kamada M., Sato G. 1983; Comparative sequence analysis of the inverted terminal repetition in the genomes of animal and avian adenoviruses. Virology 125:491–495
    [Google Scholar]
  23. Sira S., Abouhaidar M. G., Liu Y. -C., Campbell J. B. 1987; Multiple reiteration of a 40-bp nucleotide sequence in the inverted terminal repeat of the genome of a canine adenovirus. Virology 159:76–83
    [Google Scholar]
  24. Spibey N., McLory R. S., Cavanagh H. M. A. 1989; Identification and nucleotide sequence of the early region 1 from canine adenovirus types 1 and 2. Virus Research 14:241–256
    [Google Scholar]
  25. Sprengel J., Schmitz B., Heuss-Neitzel D., Zock C., Doerfler W. 1994; Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis. Journal of Virology 68:379–389
    [Google Scholar]
  26. Vrati S., Brookes D. E., Strike P., Khatri A., Boyle D. B., Both G. W. 1996; Unique genome arrangement of an ovine adenovirus : identification ofnewproteins andproteinase cleavage sites. Virology 220:186–199
    [Google Scholar]
  27. Wold W. S. M., Hermiston T. W., Tollefson A. E. 1994; Adenovirus proteins that subvert host defences. Trends in Microbiology 2:437–443
    [Google Scholar]
/content/journal/jgv/10.1099/0022-1317-78-4-873
Loading
/content/journal/jgv/10.1099/0022-1317-78-4-873
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error