RT Journal Article SR Electronic(1) A1 Peng, Gao A1 Hongo, Seiji A1 Kimura, Hiroshi A1 Muraki, Yasushi A1 Sugawara, Kanetsu A1 Kitame, Fumio A1 Numazaki, Yoshio A1 Suzuki, Hiroshi A1 Nakamura, KiyotoYR 1996 T1 Frequent occurrence of genetic reassortment between influenza C virus strains in nature JF Journal of General Virology, VO 77 IS 7 SP 1489 OP 1492 DO https://doi.org/10.1099/0022-1317-77-7-1489 PB Microbiology Society, SN 1465-2099, AB Previous studies of the haemagglutinin-esterase (HE) genes of various influenza C isolates suggested the existence of three distinct virus lineages (C/Yamagata/26/81-, C/Aichi/1/81- and C/Mississippi/80-related lineages) in Japan in the 1980s. Here we analysed the genetic properties of three strains (C/Yamagata/5/92, C/Miyagi/3/93 and C/Miyagi/4/93) isolated in Yamagata and Sendai Cities, Japan, in 1992/1993. Comparison of total or partial nucleotide sequences of the seven RNA segments of C/Yamagata/5/92 with those of 11 previous isolates suggested that the 1992 strain is a reassortant which inherited HE, P3, NP and M genes from a C/Mississippi/80-like virus and PB2, PB1 and NS genes from a C/pig/Beijing/115/81-like virus. Furthermore, it became evident that at least two (C/England/83 and C/Yamagata/9/88) of the 11 reference strains are also reassortants., UL https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-77-7-1489