%0 Journal Article %A Peng, Gao %A Hongo, Seiji %A Kimura, Hiroshi %A Muraki, Yasushi %A Sugawara, Kanetsu %A Kitame, Fumio %A Numazaki, Yoshio %A Suzuki, Hiroshi %A Nakamura, Kiyoto %T Frequent occurrence of genetic reassortment between influenza C virus strains in nature %D 1996 %J Journal of General Virology, %V 77 %N 7 %P 1489-1492 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-77-7-1489 %I Microbiology Society, %X Previous studies of the haemagglutinin-esterase (HE) genes of various influenza C isolates suggested the existence of three distinct virus lineages (C/Yamagata/26/81-, C/Aichi/1/81- and C/Mississippi/80-related lineages) in Japan in the 1980s. Here we analysed the genetic properties of three strains (C/Yamagata/5/92, C/Miyagi/3/93 and C/Miyagi/4/93) isolated in Yamagata and Sendai Cities, Japan, in 1992/1993. Comparison of total or partial nucleotide sequences of the seven RNA segments of C/Yamagata/5/92 with those of 11 previous isolates suggested that the 1992 strain is a reassortant which inherited HE, P3, NP and M genes from a C/Mississippi/80-like virus and PB2, PB1 and NS genes from a C/pig/Beijing/115/81-like virus. Furthermore, it became evident that at least two (C/England/83 and C/Yamagata/9/88) of the 11 reference strains are also reassortants. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-77-7-1489