1887

Abstract

DBA/2 mice treated with anti-Mac1 monoclonal antibody (MAb) failed to develop encephalomyocarditis virus (EMCV)-induced diabetes and myocarditis. Virus concentrations and the number of viral RNA-positive cells in the pancreas and heart were significantly reduced in mice treated with anti-Mac1 MAb. Mac1-positive macrophages seem to be involved in EMCV-induced disease and to affect the replication of EMCV in target organs.

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/content/journal/jgv/10.1099/0022-1317-77-4-737
1996-04-01
2020-01-21
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-77-4-737
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