The relationships between different strains of mumps virus were established by determination of the sequence of the HN gene. They closely resemble those established from other portions of the genome, suggesting that the viruses are not recombinants over the areas examined. The relationships were consistent with those established by reaction with monoclonal antibodies raised against the Urabe strain, which has a similar antigenic structure to previously studied laboratory strains, and largely consistent with the specificity of the serological response of naturally infected or vaccinated human subjects.
AfzalM. A.,
PickfordA. R.,
ForseyT.,
HeathA. B.,
MinorP. D.1993; The Jeryl Lynn vaccine strain of mumps virus is a mixture of two distinct isolates. Journal of General Virology 74:917–920
AfzalM. A.,
PickfordA. R.,
YatesP. J.,
ForseyT.,
MinorP. D.1994; Matrix protein gene sequence of vaccine and vaccine-associated strains of mumps virus. Journal of General Virology 75:1169–1172
BatyD. U.,
RandallR. E.1993; Multiple amino acid substitutions in the HN protein of the paramyxovirus, SV5, are selected for in monoclonal antibody resistant mutants. Archives of Virology 131:217–224
BuynakE. B.,
HillemanM. R.1966; Live attenuated mumps virus vaccine. I. Vaccine development. Proceedings of the Society for Experimental Biology and Medicine 123:768–775
ElliotG. D.,
AfzalM. A.,
MartinS. J.,
RimaB. K.1989; Nucleotide sequence of the matrix, fusion and putative SH protein genes of mumps virus and their deduced amino acid sequences. Virus Research 12:61–75
ForseyT.,
MawnJ. A.,
YatesP. J.,
BentleyM. L.,
MinorP. D.1990; Differentiation of vaccine and wild mumps viruses using the polymerase chain reaction and dideoxynucleotide sequencing. journal of General Virology 71:987–990
ForseyT.,
HeathA. B.,
MinorP. D.1993; A European collaborative study to assess the proficiency of laboratory estimates of potency of live measles mumps and rubella trivalent vaccines. Biologicals 21:239–249
GerhardW.,
YewdellJ.,
FrankelM. E.,
LopezA. D.,
StaudtL.1980; Monoclonal antibodies against influenza virus. In Monoclonal Antibodies and Hybridomas: A New Dimension in Biological Analysis pp 317–333 Edited by
KennetR. J.,
McKeamT. J.,
BechtolK. B.
New York: Plenum Press;
GlückR.,
HoskinsJ. M.,
WegmannA.,
JustM.,
GermanierR.1986; Rubini, a new live attenuated mumps vaccine virus strain for human diploid cells. Developments in Biological Standardization 65:29–35
KövameesJ.,
NorrbyE.,
ElangoN.1989; Complete nucleotide sequence of the HN mRNA of mumps virus and comparison of paramyxovirus HN proteins. Virus Research 12:87–96
KünkelU.,
DrieselC.,
HenningU.,
GerikeE.,
WillersH.,
SchreierE.1995; Differentiation of vaccine and wild mumps viruses by polymerase chain reaction and nucleotide sequencing of the SH gene. journal of Medical Virology 45:121–126
MannG. F.,
AllisonL. M. C.,
CopelandJ. A.,
AgostiniC. F. M.,
ZuckermanA. J.1980; A simplified plaque assay system for measles virus. journal of Biological Standardization 8:219–225
örvellC.1976; Identification of paramyxovirus specific haemolysis antibodies separate from haemagglutinating inhibiting and neuraminidase inhibiting antibodies. Acta Pathologica Microbiologica et Immunologica Scandinavica Section B Microbiology 84:441
OkazakiK.,
TanabayashiK.,
TakeuchiK.,
HishiyamaM.,
OkazakiK.,
YamadaA.1992; Molecular cloning and sequence analysis of the mumps virus gene encoding the L protein and the trailer sequence. Virology 188:926–930
RydbeckR.,
LöveA.,
örvellC.,
NorrbyE.1986; Antigenic variation of envelope and internal proteins of mumps virus strains detected with monoclonal antibodies. journal of General Virology 67:281–287
ServerA. C.,
MerzD. C.,
WaxhamM. N.,
WolinskyJ. S.1982; Differences of mumps virus strains with monoclonal antibody to the HN glycoprotein. Infection and Immunity 35:179–186
TakeuchiK.,
TanabayashiK.,
HishiyamaM.,
YamadaA.,
SugiuraA.1989; Cloning and sequencing of the haemagglutinin-neuraminidase gene of mumps virus (Miyahara strain). Nucleic Acids Research 17:5840–5849
TaminA.,
RotaP. A.,
WangZ.,
HeathJ. L.,
AndersonL. J.,
BelliniW. J.1994; Antigenic analysis of current wild-type and vaccine strains of measles virus. Journal of Infectious Diseases 170:795–801
YamadaA.,
TakeuchiK.,
TanabayashiK.,
HishiyamaM.,
TakahashiY.,
SugiuraA.1990; Differentiation of the mumps vaccine strains from the wild viruses by the nucleotide sequences of the P gene. Vaccine 8:553–557
YamanishiK.,
TakahashiM.,
KuirimuraT.,
UedaS.,
MinekawnaY.,
OginoT.,
SuzukiN.,
BabaK.,
OkunoY.1970; Studies on live mumps virus vaccine. III. Evaluation of newly developed live mumps virus vaccine. Biken journal 13:157–161
YeoR. P.,
AfzalM. A.,
ForseyT.,
RimaB. K.1993; Identification of a new mumps virus lineage by nucleotide sequence analysis of the SH gene of ten different strains. Archives of Virology 128:371–377