Characterization of an established human hepatoma cell line constitutively expressing non-structural proteins of hepatitis C virus by transfection of viral cDNA

References

1. Bruix J., Barrera J. M., Calvet X., Ercilla G., Costa J., Sanchez-Tapias J. M., Ventura M., Vall M., Bruguera M., Bru C., Castillo R., Rodes J. 1989; Prevalence of antibodies to hepatitis C virus in Spanish patients with hepatocellular carcinoma and hepatic cirrhosis. Lancet ii:1004–1006
   [Google Scholar]
2. Chen C., Okayama H. 1987; High-efficiency transformation of mammalian cells by plasmid DNA. Molecular and Cellular Biology 7:2745–2752
   [Google Scholar]
3. Choo Q.-L., Kuo G., Weiner A. J., Overby L. R., Bradley D. W., Houghton M. 1989; Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244:359–362
   [Google Scholar]
4. Colombo M., Kuo G., Choo Q.-L., Donato M. F., Ninno E. D., Tommasini M. A., Dioguardi N., Houghton M. 1989; Prevalence of antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma. Lancet ii:1006–1008
   [Google Scholar]
5. Dang N. H., Torimoto, Schlossman S. F., Morimoto C. 1990; Human CD4 helper T cell activation: functional involvement of two distinct collagen receptors, 1F7 and VLA integrin family. Journal of Experimental Medicine 172:649–652
   [Google Scholar]
6. Failla C., Tomei L., de Francesco R. 1994; Both NS3 and NS4a are required for proteolytic processing of hepatitis C virus non-structural proteins. Journal of Virology 68:3753–3760
   [Google Scholar]
7. Grakoui A., McCourt D. W., Wychowski C., Feinstone S. M. Rice C. Μ. 1993a; A second hepatitis C virus-encoded proteinase. Proceedings of the National Academy of Sciences, USA 90:10583–10587
   [Google Scholar]
8. Grakoui A., McCourt D. W., Wychowski C., Feinstone S. M., Rice C. M. 1993b; Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites. Journal of Virology 67:2832–2843
   [Google Scholar]
9. Grakoui A., Wychowski C., Lin C., Feinstone S. M., Rice C. M. 1993c; Expression and identification of hepatitis C virus polyprotein cleavage products. Journal of Virology 67:1385–1395
   [Google Scholar]
10. Gutheil W. G., Subramanyam M., Flentke G. R., Sanford D. G., Munoz E., Huber B. T., Bachovchin W. W. 1994; Human immunodeficiency virus 1 tat binds to dipeptidyl aminopeptidase IV (CD26): A possible mechanism for tat′s immunosuppressive activity. Proceedings of the National Academy of Sciences, USA 91:6594–6598
    [Google Scholar]
11. Hijikata M., Mizushima H., Akagi T., Mori S., Kakiuchi N., Kato N., Tanaka T., Kimura K., Shimotohno K. 1993a; Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. Journal of Virology 67:4665–4675
    [Google Scholar]
12. Hijikata M., Mizushima H., Komoda Y., Hirowatari Y., Akagi T., Kato N., Kimura K., Shimotohno K. 1993b; Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus. Proceedings of the National Academy of Sciences, USA 90:10773–10777
    [Google Scholar]
13. Kameoka J., Tanaka T., Nojima Y., Schlossman S. F., Morimoto C. 1993; Direct association of adenosine deaminase with a T cell activation antigen, CD26. Science 261:466–469
    [Google Scholar]
14. Kato N., Hijikata M., Ootsuyama Y., Nakagawa M., Ohkoshi S., Sugimura T., Shimotohno K. 1990; Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proceedings of the National Academy of Sciences, USA 87:9524–9528
    [Google Scholar]
15. Kim D. W., Uetsuki T., Kaziro Y., Yamaguchi N., Sugano S. 1990; Use of the human elongation factor la promoter as a versatile and efficient expression system. Gene 91:217–223
    [Google Scholar]
16. Kim D.-W., Harada T., Saito I., Miyamura T. 1993; An efficient expression vector for stable expression in human liver cells. Gene 134:307–308
    [Google Scholar]
17. Kubo Y., Takeuchi K., Boonmar S., Katayama T., Choo Q.-L., Kuo G., Weiner A. W., Bradley D. W., Houghton M., Saito I., Miyamura T. 1989; A cDNA fragment of hepatitis C virus isolated from an implicated donor of post-transfusion non-A, non-B hepatitis in Japan. Nucleic Acids Research 17:10367–10372
    [Google Scholar]
18. Kunkel T. A. 1985; Rapid and efficient site-specific mutagenesis without phenotypic selection. Proceedings of the National Academy of Sciences, USA 82:488–492
    [Google Scholar]
19. Kuo G., Choo Q.-L., Alter H. J., Gitnick G. L., Redeker A. G., Purcell R. H., Miyamura T., Dienstag J. L., Alter M. J., Stevens C. E., Tegmeiier G. E., Bonino F., Colombo M., Lee W.-S., Kuo C., Berger K., Shuster F. R., Overby L. R., Bradley D. W., Houghton M. 1989; An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Science 244:362–364
    [Google Scholar]
20. Laemmli U. K. 1970; Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680–685
    [Google Scholar]
21. Manabe S., Fuke I., Tanishita O., Kaji C., Gomi Y., Yoshida S., Mori C., Takamizawa A., Yoshida I., Okayama H. 1994; Production of nonstructural proteins of hepatitis C virus requires a putative viral protease encoded by NS3. Virology 198:636–644
    [Google Scholar]
22. Matsuura Y., Harada S., Suzuki R., Watanabe Y., Inoue Y., Saito I., Miyamura T. 1992; Expression of processed envelope protein of hepatitis C virus in mammalian and insect cells. Journal of Virology 66:1425–1431
    [Google Scholar]
23. Nishioka K., Watanabe J., Furuta S., Tanaka E., Iino S., Suzuki H., Tsuji T., Yano M., Kuo G., Choo Q.-L., Houghton M., Oda T. 1991; A high prevalence of antibody to the hepatitis C virus in patients with hepatocellular carcinoma in Japan. Cancer 67:429–433
    [Google Scholar]
24. Piazza G. A., Callanan J. M., Mowery J., Hixson D. C. 1989; Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix. Biochemical Journal 262:327–334
    [Google Scholar]
25. Saito I., Oya Y., Shimojo H. 1986a; Novel RNA family structure of hepatitis B virus expressed in human cells, using helper-free adenovirus vector. Journal of Virology 58:554–560
    [Google Scholar]
26. Saito I., Stark G. R. 1986b; Charomids: cosmid vectors for efficient cloning and mapping of large or small restriction fragments. Proceedings of the National Academy of Sciences, USA 83:8664–8668
    [Google Scholar]
27. Saito I., Miyamura T., Ohbayashi A., Harada H., Katayama T., Kikuchi S., Watanabe Y., Koi S., Onji Μ., Ohta Y., Choo Q. L., Houghton M., Kuo G. 1990; Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proceedings of the National Academy of Sciences, USA 87:6547–6549
    [Google Scholar]
28. Shimizu Y. K., Iwamoto A., Huikata M., Purcell R. H., Yoshikura H. 1992; Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line. Proceedings of the National Academy of Sciences, USA 89:5477–5481
    [Google Scholar]
29. Suzuki T., Masui N., Kajino K., Saito I., Miyamura T. 1989; Detection and mapping of spliced RNA from a human hepatoma cell line transfected with the hepatitis B virus genome. Proceedings of the National Academy of Sciences, USA 86:8422–8426
    [Google Scholar]
30. Takeuchi K., Boonmar S., Kubo Y., Katayama T., Harada H., Ohbayashi A., Choo Q.-L., Kuo G., Houghton M., Saito I., Miyamura T. 1990a; Hepatitis C virus cDNA clones isolated from a healthy carrier donor implicated to post transfusion non-A, non-B hepatitis. Gene 91:287–291
    [Google Scholar]
31. Tajceuchi K., Kubo Y., Boonmar S., Watanabe Y., Katayama T., Choo Q.-L., Kuo G., Houghton M., Saito I., Miyamura T. 1990b; Nucleotide sequence of core and envelope genes of the hepatitis C virus genome derived directly from human healthy carriers. Nucleic Acids Research 18:4626
    [Google Scholar]
32. Tomei L., Failla C., Santolini E., de Francesco R., la Monica N. L. 1993; NS3 is a serine protease required for processing of hepatitis C virus polyprotein. Journal of Virology 67:4017–4026
    [Google Scholar]
33. Uetsuki T., Naito A., Nagata S., Kaziro Y. 1989; Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor lα. Journal of Biological Chemistry 246:5791–5798
    [Google Scholar]
34. Ulmer A. J., Mattern T., Feller A. C., Heymann E., Flad H. D. 1990; CD26 antigen is a surface dipeptidyl peptidase IV (DPPIV) as characterized by monoclonal antibodies clone TII-19-4-7 and 4EL1C7. Scandinavian Journal of 31:429–435
    [Google Scholar]