1887

Abstract

To determine which human respiratory syncytial virus (HRSV) P protein serine residues are modified by cellular protein kinase(s), several mutated versions of P protein were expressed in the absence of other viral proteins. Mutations at serines 232 or 232 and 237 drastically reduced the extent of phosphorylation P protein . Serine 232 is the main site of modification and is also essential for phosphorylation by casein kinase II. Additional phosphorylation was also detected in the region containing serines 116, 117 and 119.

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1995-02-01
2021-10-21
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