1887

Abstract

Papillomaviruses are ubiquitous DNA viruses affecting humans and animals and causing a variety of tumours of mucosal and cutaneous epithelia. Some of these lesions, particularly those affecting mucosal epithelia, can progress to squamous cell carcinomas. Prevention or cure of viral infection would ultimately lead to a decrease in the incidence of papillomavirus-associated cancers. Using recombinant proteins, we have developed prophylactic and therapeutic vaccines against bovine papillomavirus type 4, a mucosal papillomavirus implicated in cancer of the alimentary canal in cattle; similar possibilities exist for the human mucosal papillomaviruses.

Erratum

An erratum has been published for this content:
Prophylactic and therapeutic vaccination against a mucosal papillomavirus
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1993-06-01
2021-10-25
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References

  1. Campo M. S. 1991; Vaccination against papillomavirus. Cancer Cells 3:421–426
    [Google Scholar]
  2. Campo M. S., Jarrett W. F. H. 1986; Papillomavirus infection in cattle: viral and chemical cofactors in naturally occurring and experimentally induced tumours. In Papillomaviruses: Ciba Foundation Symposium 120 pp. 117–135 Edited by Evered D., Clark S. New York: John Wiley;
    [Google Scholar]
  3. Campo M. S., Moar M. H., Jarrett W. F. H., Laird H. M. 1980; A new papillomavirus associated with alimentary cancer in cattle. Nature, London 286:180–182
    [Google Scholar]
  4. Chen L., Thomas E. K., Hu S.-L., Hellstrom I., Hellstrom K. E. 1991; Human papillomavirus type 16 nucleoprotein E7 is a tumor rejection antigen. Proceedings of the National Academy of Sciences, U.S.A. 88:110–114
    [Google Scholar]
  5. Christensen N. D., Kreider J. W., Kan N. C., DiAngelo S. L. 1991; The open reading frame L2 of cottontail rabbit papillomavirus contains antibody-inducing neutralizing epitopes. Virology 181:572–579
    [Google Scholar]
  6. de Villiers E.-M. 1989; Heterogeneity of the human papillomavirus group. Journal of Virology 63:4898–4903
    [Google Scholar]
  7. Dollard S. C., Wilson J. L., Demeret L. M., Bonnez W., Reichman R. C., Broker T. R., Chow L. T. 1992; Production of human papillomavirus and modulation of the infectious program in epithelial raft cultures. Genes and Development 6:1131–1142
    [Google Scholar]
  8. Evans C. A., Gorman L. R., Ito Y., Weiser R. S. 1962; Antitumor immunity in the Shope papilloma-carcinoma complex of rabbits. I. Papilloma regression induced by homologous and autologous tissue vaccines. Journal of the National Cancer Institute 29:277–285
    [Google Scholar]
  9. Ghim S.-J., Jenson A. B., Schlegel R. 1992; HPV-1 LI protein expressed in COS cells displays conformational epitopes found on intact virions. Virology 190:548–552
    [Google Scholar]
  10. Jackson M. E., Pennie W. D., McCaffery R. E., Smith K. T., Grindlay G. J., Campo M. S. 1991; The B subgroup bovine papillomaviruses lack an identifiable E6 open reading frame. Molecular Carcinogenesis 4:382–387
    [Google Scholar]
  11. Jaggar R. T., Pennie W. D., Smith K. T., Jackson M. E., Campo M. S. 1990; Cooperation between bovine papillomavirus type 4 and ras in the morphological transformation of primary bovine fibroblasts. Journal of General Virology 71:3041–3046
    [Google Scholar]
  12. Jarrett W. F. H. 1985; The natural history of bovine papillomavirus infection. In Advances in Viral Oncology vol. 5 pp. 83–102 Edited by Klein G. New York: Raven Press;
    [Google Scholar]
  13. Jarrett W. F. H., Campo M. S., O’Neil B. W., Laird H. M., Coggins L. W. 1984; A novel bovine papillomavirus (BPV-6) causing true epithelial papillomas of the mammary gland skin: a member of a proposed new subgroup. Virology 136:255–264
    [Google Scholar]
  14. Jarrett W. F. H., O’Neil B. W., Gaukroger J. M., Smith K. T., Laird H. M., Campo M. S. 1990a; Studies on vaccination against papillomaviruses: the immunity after infection and vaccination with bovine papillomaviruses of different types. Veterinary Record 126:473–475
    [Google Scholar]
  15. Jarrett W. F. H., O’Neil B. W., Gaukroger J. M., Laird H. M., Smith K. T., Campo M. S. 1990b; Studies on vaccination against papillomaviruses: a comparison of purified virus, tumour extract and transformed cells in prophylactic vaccination. Veterinary Record 126:449–452
    [Google Scholar]
  16. Jarrett W. F. H., Smith K. T., O’Neil B. W., Gaukroger J. M., Chandrachud L. M., Grindlay G. J., McGarvie G. M., Campo M. S. 1991; Studies on vaccination against papillomaviruses: prophylactic and therapeutic vaccination with recombinant structural proteins. Virology 184:33–42
    [Google Scholar]
  17. Jenison S. A., Firzlaff J. M., Langenberg A., Galloway D. A. 1988; Identification of immunoreactive antigens of human papillomavirus type 6b by using Escherichia coff-expressed fusion proteins. Journal of Virology 62:2115–2123
    [Google Scholar]
  18. Kreider J. W., Howett M. K., Lill N. L., Bartlett G. L., Zaino R. J., Sedlacek T. V., Mortel R. 1986; In vivo transformation of human skin with human papillomavirus type 11 from condylomata acuminata. Journal of Virology 59:369–376
    [Google Scholar]
  19. Lin Y.-L., Borenstein L. A., Selvakumar R., Ahmed R., Wettstein F. O. 1992; Effective vaccination against papilloma development by immunization with LI or L2 structural proteins of cottontail rabbit papillomavirus. Virology 187:612–619
    [Google Scholar]
  20. McLean C. S., Sterling J. S., Mowat J., Nash A. A., Stanley M. A. 1993; Delayed-type hypersensitivity response to the human papillomavirus type 16 E7 protein in a mouse model. Journal of General Virology 74:239–245
    [Google Scholar]
  21. Meneguzzi G., Cerni C., Kieny M. P., Lathe R. 1991; Immunization against human papillomavirus type 16 tumor cells with recombinant vaccinia viruses expressing E6 and E7. Virology 181:62–69
    [Google Scholar]
  22. Meyers C., Frattini M. G., Hudson J. B., Laimins L. A. 1992; Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation. Science 257:971–973
    [Google Scholar]
  23. Olson C., Segre D., Skidmore L. V. 1959; Further observations on immunity to bovine cutaneous papillomatosis. American Journal of Veterinary Research 21:233–242
    [Google Scholar]
  24. Pennie W. D., Grindlay G. J., Cairney M., Campo M. S. 1993; Analysis of the transforming functions of bovine papillomavirus type 4. Virology 193:614–620
    [Google Scholar]
  25. Ruther U., Muller-Hill B. 1983; Easy identification of cDNA clones. EMBO Journal 2:1791–1794
    [Google Scholar]
  26. Smith B. D., Johnson K. S. 1988; Single step purification of polypeptides expressed in Escherichia coli as fusions with glutathione-S-transferase. Gene 67:31–40
    [Google Scholar]
  27. Stacey S. N., Bartholomew J. S., Ghosh A., Stern P. L., Mackett M., Arrand J. R. 1992; Expression of human papillomavirus type 16 E6 protein by recombinant baculovirus for use and detection of anti-E6 antibodies in human sera. Journal of General Virology 73:2337–2345
    [Google Scholar]
  28. Steinberg B. M. 1987; Laryngeal papillomas. Clinical aspects and in vitro studies. In The Papovaviridae vol 2 pp. 265–292 Edited by Salzman N. P., Howley P. M. New York: Plenum Press;
    [Google Scholar]
  29. Sterling J., Stanley M., Gatward G., Minson T. 1990; Production of human papillomavirus type 16 virions in a keratinocyte cell line. Journal of Virology 64:6305–6307
    [Google Scholar]
  30. Teichman L. B., LaPorta R. F. 1987; The expression of papillomaviruses in epithelial cells. In The Papovaviridae vol. 2 pp. 109–139 Edited by Salzman N. P., Howley P. M. New York: Plenum Press;
    [Google Scholar]
  31. Tindle R. W., Smith J. A., Geysen H. M., Selvey L. A., Frazer I. H. 1990; Identification of B epitopes in human papillomavirus type 16 E7 open reading frame protein. Journal of General Virology 71:1347–1354
    [Google Scholar]
  32. zur Hausen H. 1991; Human papillomaviruses in the pathogenesis of anogenital cancer. Virology 184:9–13
    [Google Scholar]
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