Full text loading...
We studied the effect of two cytokines, basic fibroblastic growth factor (bFGF) and transforming growth factor beta (TGF-β) on human cytomegalovirus (HCMV) replication in cultured human lung fibroblasts. We show that TGF-β increases HCMV production, probably by a transcriptional mechanism, and that bFGF represses HCMV replication in a dose-dependent manner. These actions were antagonistic and the mechanisms involved were independent of the effects of these factors on cell DNA synthesis and proliferation.
Article metrics loading...
Full text loading...
References
Data & Media loading...