@article{mbs:/content/journal/jgv/10.1099/0022-1317-73-2-467, author = "Smibert, Craig A. and Johnson, David C. and Smiley, James R.", title = "Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41", journal= "Journal of General Virology", year = "1992", volume = "73", number = "2", pages = "467-470", doi = "https://doi.org/10.1099/0022-1317-73-2-467", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-73-2-467", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "The virion-induced host shutoff product of the herpes simplex virus UL41 gene is required for shutoff of host translation and degradation of cellular mRNAs. We employed a rabbit antipeptide antiserum to identify a 58K UL41-related phosphoprotein in infected cells. We also provide evidence that this protein is a component of the virus particle, consistent with its role in virion-induced shutoff.", }