1887

Abstract

An epitope involved in neutralization of foot-and-mouth disease virus (FMDV) of subtype C was generated by a single amino acid replacement in VP1 of FMDV of subtype C. The replacement [Ser (139) → Ile, in the immunodominant site A] was consistently found in those FMDV C Santa Pau-Sp/70 mutants resistant to neutralization by monoclonal antibody (MAb) SD6 (specific for most C viruses) that acquired the capacity to be neutralized by MAb 7AB5 (specific for C viruses).

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/content/journal/jgv/10.1099/0022-1317-73-1-213
1992-01-01
2019-10-21
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http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-73-1-213
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