Introduction. The ‘Highlights’ review has become an annual feature of this Journal, and its aim is to present an overview of selected advances in virology made during the previous year. We stress that the choice of topics is highly subjective and does not purport to be exhaustive, but reflects the interests of the authors concerned. We start with a section dealing with newly characterized animal and plant viruses, and then move on to deal with complete virual genome sequences. Next we report on human immunodeficiency virus and the structure of CD4, advances in baculovirology, the manipulation of RNA virus genomes, novel mechanisms of resistance to virus infection in plants, and finish with a section on the use of transgenic mice in virological research.


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