%0 Journal Article %A Roy, P. %A Hirasawa, T. %A Fernandez, M. %A Blinov, V. M. %A Rodrique, Sanchez-Vixcain J. M. %T The complete sequence of the group-specific antigen, VP7, of African horsesickness disease virus serotype 4 reveals a close relationship to bluetongue virus %D 1991 %J Journal of General Virology, %V 72 %N 6 %P 1237-1241 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-72-6-1237 %I Microbiology Society, %X The complete sequence of the S7 RNA that codes for the major group-specific coat protein, VP7, of African horsesickness virus serotype 4 (AHSV-4) was determined from cDNA analyses and found to be 1179 nucleotides in length. One single open reading frame of 353 codons was observed defining a protein of M r 38107 with a net charge of -1.5 at neutral pH. Comparison of the AHSV-4 VP7 sequence with that of bluetongue virus serotype 10 revealed an overall similarity of 44%, with the amino- and carboxy-terminal regions exhibiting the greatest levels of homology. In addition, potential secondary structures of the terminal sequences of the S7 RNA segments of AHSV-4 and BTV serotypes 10, 13 and 17 are presented. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-72-6-1237