@article{mbs:/content/journal/jgv/10.1099/0022-1317-72-5-1105, author = "Kawamura, Mikiko and Hayashi, Masanobu and Furuichi, Tatsuya and Nonoyama, Meihan and Isogai, Emiko and Namioka, Shigeo", title = "The inhibitory effects of oligonucleotides, complementary to Marek's disease virus mRNA transcribed from the BamHI-H region, on the proliferation of transformed lymphoblastoid cells, MDCC-MSB1", journal= "Journal of General Virology", year = "1991", volume = "72", number = "5", pages = "1105-1111", doi = "https://doi.org/10.1099/0022-1317-72-5-1105", url = "https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-72-5-1105", publisher = "Microbiology Society", issn = "1465-2099", type = "Journal Article", abstract = "An oligonucleotide complementary to the splice donor sequence of the 1.8 kb gene family produced from the BamHI-H region of Marek's disease virus (MDV) DNA inhibited the proliferation of the MDV-derived lymphoblastoid cell line, MDCC-MSB1 (MSB-1), but not that of the avian lymphoid leukosis-derived lymphoblastoid cell line, LSCC-BK3. Colony formation in soft agar was also inhibited by treatment of MSB-1 cells with the antisense oligonucleotide. It is hypothesized that expression of the 1.8 kb gene family produced from the BamHI-H region is directly associated with the maintenance of the tumorigenic state of transformed Marek's disease-derived lymphoblastoid cells.", }