%0 Journal Article %A Curran, M. D. %A Clarke, D. K. %A Rima, B. K. %T The nucleotide sequence of the gene encoding the attachment protein H of canine distemper virus %D 1991 %J Journal of General Virology, %V 72 %N 2 %P 443-447 %@ 1465-2099 %R https://doi.org/10.1099/0022-1317-72-2-443 %I Microbiology Society, %X The sequence of the H gene and flanking sequences in the F and L genes of canine distemper virus (CDV) have been determined. The H gene of CDV (1946 nucleotides) contains one large open reading frame starting at position 21 and terminating at position 1835, encoding a protein of 604 amino acid residues. This protein contains three potential glycosylation sites in the extracellular domain and, like all other paramyxoviruses, a N-terminal membrane-spanning hydrophobic anchor domain. The deduced H protein sequence shows an identity of 36% with rinderpest virus (RPV) and measles virus (MV). The identities at the nucleotide level are higher (RPV 52% and MV 53%). The amino acid sequence shows conservation of all the structural determinants with the H proteins of MV and RPV. The data also show that CDV is evolutionarily equidistant to RPV and MV with respect to the H gene. %U https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-72-2-443