1887

Abstract

A one base change (adenine at position 7861) in the long control region (LCR) of the prototype sequence of human papillomavirus type 16 was reported. With this correction, a new E2-binding site was revealed, 111 bp and 143 bp upstream from the TATA box and P97, respectively, and 105 bp downstream of the keratinocyte-dependent enhancer. An A to C mutation at position 41 was found in a patient with invasive carcinoma. This mutation falls within an E2-binding site.

Loading

Article metrics loading...

/content/journal/jgv/10.1099/0022-1317-72-10-2573
1991-10-01
2022-10-04
Loading full text...

Full text loading...

/deliver/fulltext/jgv/72/10/JV0720102573.html?itemId=/content/journal/jgv/10.1099/0022-1317-72-10-2573&mimeType=html&fmt=ahah

References

  1. Anderson M. L. M., Young B. D. 1985; Quantitative filter hybridization. In Nucleic Acid Hybridization: A Practical Approach pp 73–113 Edited by Hames B. D., Higgins S. J. Oxford: IRL Press;
    [Google Scholar]
  2. Bedell M. A., Jones K. H., Laimins L. A. 1987; The E6-E7 region of human papillomavirus type 18 is sufficient for transformation of NIH 3T3 and Rat-1 cells. Journal of Virology 61:3635–3640
    [Google Scholar]
  3. Boshart M., Gissmann L., Ikenberg H., Kleinheinz W., Scheurlen W., zur Hausen H. 1984; A new type of papillomavirus DNA and its presence in genital cancer biopsies and in cell lines derived from cervical carcinoma. EMBO Journal 3:1151–1157
    [Google Scholar]
  4. Bubb V., McCance D. J., Schlegel R. 1988; DNA sequence of the HPV-16 E5 ORF and the structural conservation of its encoded protein. Virology 163:243–246
    [Google Scholar]
  5. Choo K. B., Pan C. C., Han S. H. 1987a; Integration of human papillomavirus type 16 into cellular DNA of cervical carcinoma: preferential deletion of the E2 gene and invariable retention of the long control region and the E6/E7 open reading frames. Virology 161:259–261
    [Google Scholar]
  6. Choo K. B., Pan C. C., Liu L. M., Ng H. T., Chen C. P., Lee Y. N., Chao C. F., Meng C. L., Yeh M. Y., Han S. H. 1987b; Presence of episomal and integrated human papillomavirus DNA sequences in cervical carcinoma. Journal of Medical Virology 21:101–107
    [Google Scholar]
  7. Choo K. B., Lee H. H., Pan C. C., Wu S. M., Liew L. N., Cheung W. F., Han S. H. 1988; Sequence duplication and internal deletion in the integrated human papillomavirus type 16 genome cloned from a cervical carcinoma. Journal of Virology 62:1659–1666
    [Google Scholar]
  8. Cripe T. P., Haugen T. H., Turk J. P., Tabatabai F., Schmid P. G. III, Dürst M., Gissmann L., Roman A., Turek L. P. 1987; Transcriptional regulation of the human papillomavirus 16 E6-E7 promoter by a keratinocyte-dependent enhancer, and by viral E2 trans-activator and repressor gene products: implication for cervical carcinogenesis. EMBO Journal 6:3745–3753
    [Google Scholar]
  9. Dürst M., Gissmann L., Ikenberg H., zur Hausen H. 1983; A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions. Proceedings of the National Academy of Sciences, U.S.A 80:3812–3815
    [Google Scholar]
  10. Gloss B., Bernard H. U., Seedorf K., Klock G. 1987; The upstream regulatory region of the human papillomavirus-16 contains an E2 protein independent enhancer which is specific for cervical carcinoma cells and regulated by glucocorticoid hormones. EMBO Journal 6:3735–3743
    [Google Scholar]
  11. Gloss B., Chong T., Bernard H. U. 1989; Numerous nuclear proteins bind the long control region of human papillomavirus type 16: a subset of 6 of 23 DNase I-protected segments coincides with the location of the cell-type-specific enhancer. Journal of Virology 63:1142–1152
    [Google Scholar]
  12. Green P. M., Bentley D. R., Mibashan R. S., Nilson I. M., GlANNELLl F. 1989; Molecular pathology of haemophilia B. EMBO Journal 8:1067–1072
    [Google Scholar]
  13. Kanda T., Watanabe S., Yoshiike K. 1988; Immortalization of primary rat cells by human papillomavirus type 16 subgenomic DNA fragments controlled by the SV40 promoter. Virology 165:321–325
    [Google Scholar]
  14. Kennedy I. M., Simpson S., Macnab J. C. M., Clements J. B. 1987; Human papillomavirus type 16 DNA from a vulvar carcinoma in situ is present as head-to-tail dimeric episomes with a deletion in the non-coding region. Journal of General Virology 68:451–462
    [Google Scholar]
  15. Kerem B. S., Rommens J. M., Buchanan J. A., Markiewicz D., Cox T. K., Chakravarti A., Buchwald M., Tsui L. C. 1989; Identification of the cystic fibrosis gene: genetic analysis. Science 245:1073–1080
    [Google Scholar]
  16. Old J. M. 1986; Fetal DNA analyses. In Human Genetic Diseases: A Practical Approach pp 1–17 Edited by Davies K. E. Oxford: IRL Press;
    [Google Scholar]
  17. Pater M. M., Pater A. 1985; Human papillomavirus types 16 and 18 sequences in carcinoma cell lines of the cervix. Virology 145:313–318
    [Google Scholar]
  18. Phelps W. C., Howley P. M. 1987; Transcriptional transactivation by the human papillomavirus type 16 E2 product. Journal of Virology 61:1630–1638
    [Google Scholar]
  19. Pirisi L., Yasumoto S., Feller M., Doniger J., DiPaolo J. A. 1987; Transformation of human fibroblasts and keratinocytes with human papillomavirus type 16 DNA. Journal of Virology 61:1061–1066
    [Google Scholar]
  20. Popescu N. C., Amsbaugh S. C., DiPaolo J. A. 1987; Human papillomavirus type 18 DNA is integrated at a single chromosome site in cervical carcinoma cell line SW 756. Journal of Virology 51:1682–1685
    [Google Scholar]
  21. Saiki R. K., Gelfand D. M., Stoffel S., Scharf S. J., Higuchi R., Horn G. T., Mullis K. B., Erlich H. A. 1988; Primer directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487–491
    [Google Scholar]
  22. Sambrook J., Fritsch E. F., Maniatis T. 1989a; Extraction and purification of plasmid DNA. In Molecular Cloning: A Laboratory Manual vol 1 pp 1.21–1.53 Edited by Nolan C. New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  23. Sambrook J., Fritsch E. F., Maniatis T. 1989b; Strategies for cloning in plasmid vectors. In Molecular Cloning: A Laboratory Manual vol 1 pp 1.70–1.73 Edited by Nolan C. New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  24. Sambrook J., Fritsch E. F., Maniatis T. 1989b; Strategies for cloning in plasmid vectors. In Molecular Cloning: A Laboratory Manual vol 1 pp 1.70–1.73 Edited by Nolan C. New York: Cold Spring Harbor Laboratory;
    [Google Scholar]
  25. Sanger F., Nicklen S., Coulson A. R. 1977; DNA sequencing with chain-terminating inhibitors. Proceedings of the National Academy of Sciences, U.S.A 74:5463–5467
    [Google Scholar]
  26. Seedorf K., Krammer G., Dürst M., Suhai S., Rowekamp W. G. 1985; Human papillomavirus type 16 DNA sequence. Virology 145:181–185
    [Google Scholar]
  27. Shirasawa H., Tomita Y., Sekiya S., Takamizawa H., Simizu B. 1987; Integration and transcription of human papillomavirus type 16 and 18 sequences in cell lines derived from cervical carcinomas. Journal of General Virology 68:583–591
    [Google Scholar]
  28. Smotkin D., Wettstein F. O. 1986; Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer derived cell line and identification of the E7 protein. Proceedings of the National Academy of Sciences, U.S.A 83:4680–4684
    [Google Scholar]
  29. Tidy J., Farrell P. J. 1989; Retraction: human papillomavirus subtype 16b. Lancet ii:1535
    [Google Scholar]
  30. Tidy J., Vousden K. H., Mason P., Farrell P. J. 1989a; A novel deletion within the upstream regulatory region of episomal human papillomavirus type 16. Journal of General Virology 70:999–1004
    [Google Scholar]
  31. Tidy J. A., Vousden K. H., Farrell P. J. 1989b; Relation between infection with a subtype of HPV 16 and cervical neoplasia. Lancet i:1225–1227
    [Google Scholar]
  32. Wagatsuma M., Hashimoto K., Matsukura T. 1990; Analysis of integrated human papillomavirus type 16 DNA in cervical cancers: amplification of viral sequences together with cellular flanking sequences. Journal of Virology 64813–821
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/0022-1317-72-10-2573
Loading
/content/journal/jgv/10.1099/0022-1317-72-10-2573
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error